Literature DB >> 15337572

On-line aSi portal imaging of implanted fiducial markers for the reduction of interfraction error during conformal radiotherapy of prostate carcinoma.

Peter W M Chung1, Tara Haycocks, Tanya Brown, Zoe Cambridge, Valerie Kelly, Hamideh Alasti, David A Jaffray, Charles N Catton.   

Abstract

PURPOSE: An on-line system to ensure accuracy of daily setup and therapy of the prostate has been implemented with no equipment modification required. We report results and accuracy of patient setup using this system. METHODS AND MATERIALS: Radiopaque fiducial markers were implanted into the prostate before radiation therapy. Lateral digitally reconstructed radiographs (DRRs) were obtained from planning CT data. Before each treatment fraction, a lateral amorphous silicon (aSi) portal image was acquired and the position of the fiducial markers was compared to the DRRs using chamfer matching. Couch translation only was used to account for marker position displacements, followed by a second lateral portal image to verify isocenter position. Residual displacement data for the aSi and previous portal film systems were compared.
RESULTS: This analysis includes a total of 239 portal images during treatment in 17 patients. Initial prostate center of mass (COM) displacements in the superior, inferior, anterior, and posterior directions were a maximum of 7 mm, 9 mm, 10 mm and 11 mm respectively. After identification and correction, prostate COM displacements were <3 mm in all directions. The therapists found it simple to match markers 88% of the time using this system. Treatment delivery times were in the order of 9 min for patients requiring isocenter adjustment and 6 min for those who did not.
CONCLUSIONS: This system is technically possible to implement and use as part of an on-line correction protocol and does not require a longer than standard daily appointment time at our center with the current action limit of 3 mm. The system is commercially available and is more efficient and user-friendly than portal film analysis. It provides the opportunity to identify and accommodate interfraction organ motion and may also permit the use of smaller margins during conformal prostate radiotherapy. Further integration of the system such as remote table control would improve efficiency.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15337572     DOI: 10.1016/j.ijrobp.2004.03.038

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  24 in total

1.  Electronic portal imaging vs kilovoltage imaging in fiducial marker image-guided radiotherapy for prostate cancer: an analysis of set-up uncertainties.

Authors:  S Gill; J Thomas; C Fox; T Kron; A Thompson; S Chander; S Williams; K H Tai; G Duchesne; F Foroudi
Journal:  Br J Radiol       Date:  2011-10-05       Impact factor: 3.039

Review 2.  Technological advances in radiation therapy for prostate cancer.

Authors:  Mehee Choi; Arthur Y Hung
Journal:  Curr Urol Rep       Date:  2010-05       Impact factor: 3.092

3.  Phantom measurements to quantify the accuracy of a commercially available cone-beam CT gray-value matching algorithm using multiple Fiducials.

Authors:  Frederick Marc Köhler; Judit Boda-Heggemann; Beate Küpper; Dirk Wolff; Hansjörg Wertz; Frank Lohr; Frederik Wenz
Journal:  Strahlenther Onkol       Date:  2009-02-18       Impact factor: 3.621

4.  Prostate intrafraction motion evaluation using kV fluoroscopy during treatment delivery: a feasibility and accuracy study.

Authors:  Justus Adamson; Qiuwen Wu
Journal:  Med Phys       Date:  2008-05       Impact factor: 4.071

5.  Intensity-modulated radiotherapy (IMRT) to prostate and pelvic nodes-is pelvic lymph node coverage adequate with fiducial-based image-guided radiotherapy?

Authors:  G Eminowicz; C Dean; O Shoffren; N Macdougall; P Wells; R Muirhead
Journal:  Br J Radiol       Date:  2014-03-20       Impact factor: 3.039

6.  Residual translational and rotational errors after kV X-ray image-guided correction of prostate location using implanted fiducials.

Authors:  Reinhold Graf; Dirk Boehmer; Volker Budach; Peter Wust
Journal:  Strahlenther Onkol       Date:  2010-09-30       Impact factor: 3.621

7.  Planning target volume margins for prostate radiotherapy using daily electronic portal imaging and implanted fiducial markers.

Authors:  David Skarsgard; Pat Cadman; Ali El-Gayed; Robert Pearcey; Patricia Tai; Nadeem Pervez; Jackson Wu
Journal:  Radiat Oncol       Date:  2010-06-10       Impact factor: 3.481

8.  A prospective study on pain score with transperineal prostatic gold seed fiducial implantation under local anesthetic alone.

Authors:  Colin I Tang; Perakaa Sethukavalan; Patrick Cheung; Gerard Morton; Geordi Pang; D Andrew Loblaw
Journal:  Can Urol Assoc J       Date:  2013 Mar-Apr       Impact factor: 1.862

9.  Comparison of various online IGRT strategies: The benefits of online treatment plan re-optimization.

Authors:  Derek Schulze; Jian Liang; Di Yan; Tiezhi Zhang
Journal:  Radiother Oncol       Date:  2008-10-29       Impact factor: 6.280

10.  An assessment of PTV margin based on actual accumulated dose for prostate cancer radiotherapy.

Authors:  Ning Wen; Akila Kumarasiri; Teamour Nurushev; Jay Burmeister; Lei Xing; Dezhi Liu; Carri Glide-Hurst; Jinkoo Kim; Hualiang Zhong; Benjamin Movsas; Indrin J Chetty
Journal:  Phys Med Biol       Date:  2013-10-18       Impact factor: 3.609

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.