PURPOSE: To evaluate central and peripheral corneal sensitivity (CS) in relation to age. METHODS: Five hundred eyes of 320 healthy subjects (185 males and 135 females) were examined. The age of participants ranged from 20 to 90 years. All subjects were divided into 3 groups according to age. CS was assessed with the Cochet-Bonnet esthesiometer in the central cornea and in 8 peripheral points. The averages were used as the values of central and peripheral CS. RESULTS: In the young population, CS was equal in both examined zones (p > 0.05); although, with respect to the periphery after the fifth decade, it was significantly higher in the centre (p < 0.05). Both central and peripheral sensitivity decreased with age (p < 0.05), and such variations are represented by parabolic curves. No differences were observed between males and females. CONCLUSIONS: The age-related decrement of CS involves at first the corneal periphery and successively spreads toward the central zone. Topographical distribution and age-related modifications should be considered in clinical investigations of CS, especially in patients who underwent any corneal surgical procedure. Copyright 2004 S. Karger AG, Basel
PURPOSE: To evaluate central and peripheral corneal sensitivity (CS) in relation to age. METHODS: Five hundred eyes of 320 healthy subjects (185 males and 135 females) were examined. The age of participants ranged from 20 to 90 years. All subjects were divided into 3 groups according to age. CS was assessed with the Cochet-Bonnet esthesiometer in the central cornea and in 8 peripheral points. The averages were used as the values of central and peripheral CS. RESULTS: In the young population, CS was equal in both examined zones (p > 0.05); although, with respect to the periphery after the fifth decade, it was significantly higher in the centre (p < 0.05). Both central and peripheral sensitivity decreased with age (p < 0.05), and such variations are represented by parabolic curves. No differences were observed between males and females. CONCLUSIONS: The age-related decrement of CS involves at first the corneal periphery and successively spreads toward the central zone. Topographical distribution and age-related modifications should be considered in clinical investigations of CS, especially in patients who underwent any corneal surgical procedure. Copyright 2004 S. Karger AG, Basel
Authors: Mitra Tavakoli; Maryam Ferdousi; Ioannis N Petropoulos; Julie Morris; Nicola Pritchard; Andrey Zhivov; Dan Ziegler; Danièle Pacaud; Kenneth Romanchuk; Bruce A Perkins; Leif E Lovblom; Vera Bril; J Robinson Singleton; Gordon Smith; Andrew J M Boulton; Nathan Efron; Rayaz A Malik Journal: Diabetes Care Date: 2015-01-29 Impact factor: 19.112