| Literature DB >> 15324908 |
Anna Tevyashova1, Ferenc Sztaricskai, Gyula Batta, Pál Herczegh, András Jeney.
Abstract
The reaction of the anthracycline glycoside antibiotics 1-3 with the squaric acid ester 4 gave the squaric acid amide esters 5-7 under neutral conditions, whereas over pH7 the products are the symmetric diamides (8, 9, 11, and 12). Of the prepared compounds 11 was the most active on MCF-7 human mammary adenocarcinoma cells.Entities:
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Year: 2004 PMID： 15324908 DOI： 10.1016/j.bmcl.2004.06.072
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823