Emerging technologies in biocompatible surface modifying additives: quest for physiologic cardiopulmonary bypass.

Modification of polymer surfaces to achieve a surface with enhanced compatibility is an important means of obtaining improved biomaterials. The molecular design of the novel technologies is carried out with attention to create a biomembrane-mimicking surface on medical devices. This review focuses on the comparison of the chemical composition of recent novel surface modifying additives and coating technologies, their biomaterial evaluation and clinical efficacy under the scope of our previous studies and current literature.