OBJECTIVE: To assess the reliability and validity of a brief measure of quality of life recently developed by the World Health Organization, the WHOQOL-BREF, and to examine its association with a variety of clinical and sociodemographic factors in older depressed patients. DESIGN: Cross-sectional study. METHODS: Older depressed patients (N=41) underwent diagnostic assessment using the Composite International Diagnostic Interview (CIDI) and were independently assessed on a variety of measures including the WHOQOL-BREF (a 26-item self-report questionnaire generating four domain scores), Hamilton Depression Rating Scale (HAM-D); Geriatric Depression Scale (GDS); Mini-mental State Examination (MMSE); Modified Barthel Index (MBI); Instrumental activities of daily living (IADL), and measures of physical health status and social relationships. Estimates of inter-rater and test-retest reliability, and concurrent validity were made. RESULTS: 39 subjects completed the study. The majority of subjects (94.9%) received a diagnosis of DSM-IV Major Depressive Disorder. Levels of comorbidity were high. Three of the four domains of the WHOQOL-BREF (Physical, Psychological and Environment domains) demonstrated satisfactory reliability and validity. However, the Social Relationships domain exhibited poor validity. Quality of life scores were strongly correlated with severity of depression, number of self-reported physical symptoms and self-assessed general health status. There was no relationship between diagnostic comorbidity and quality of life scores. CONCLUSIONS: The WHOQOL-BREF was successfully administered to older depressed patients although the concurrent validity of one of its four domains was poor. Quality of life scores were strongly correlated with severity of depression, raising the issue of measurement redundancy.
OBJECTIVE: To assess the reliability and validity of a brief measure of quality of life recently developed by the World Health Organization, the WHOQOL-BREF, and to examine its association with a variety of clinical and sociodemographic factors in older depressedpatients. DESIGN: Cross-sectional study. METHODS: Older depressedpatients (N=41) underwent diagnostic assessment using the Composite International Diagnostic Interview (CIDI) and were independently assessed on a variety of measures including the WHOQOL-BREF (a 26-item self-report questionnaire generating four domain scores), Hamilton Depression Rating Scale (HAM-D); Geriatric Depression Scale (GDS); Mini-mental State Examination (MMSE); Modified Barthel Index (MBI); Instrumental activities of daily living (IADL), and measures of physical health status and social relationships. Estimates of inter-rater and test-retest reliability, and concurrent validity were made. RESULTS: 39 subjects completed the study. The majority of subjects (94.9%) received a diagnosis of DSM-IV Major Depressive Disorder. Levels of comorbidity were high. Three of the four domains of the WHOQOL-BREF (Physical, Psychological and Environment domains) demonstrated satisfactory reliability and validity. However, the Social Relationships domain exhibited poor validity. Quality of life scores were strongly correlated with severity of depression, number of self-reported physical symptoms and self-assessed general health status. There was no relationship between diagnostic comorbidity and quality of life scores. CONCLUSIONS: The WHOQOL-BREF was successfully administered to older depressedpatients although the concurrent validity of one of its four domains was poor. Quality of life scores were strongly correlated with severity of depression, raising the issue of measurement redundancy.
Authors: Maria Christina Dehoust; Holger Schulz; Martin Härter; Jana Volkert; Susanne Sehner; Anna Drabik; Karl Wegscheider; Alessandra Canuto; Kerstin Weber; Mike Crawford; Alan Quirk; Luigi Grassi; Chiara DaRonch; Manuel Munoz; Berta Ausin; Anna Santos-Olmo; Arieh Shalev; Ora Rotenstein; Yael Hershkowitz; Jens Strehle; Hans-Ulrich Wittchen; Sylke Andreas Journal: Int J Methods Psychiatr Res Date: 2017-02-01 Impact factor: 4.035
Authors: Young-Eun Jung; Ho-Jun Seo; Hoo Rim Song; Young Sup Woo; Hyeon-Woo Yim; Hyung-Mo Sung; Min-Soo Lee; Jae-Min Kim; Tae-Youn Jun Journal: Qual Life Res Date: 2011-09-17 Impact factor: 4.147
Authors: Ngaire Kerse; Chris McLean; Simon A Moyes; Kathy Peri; Terence Ng; Laura Wilkinson-Meyers; Paul Brown; Nancy Latham; Martin Connolly Journal: Ann Fam Med Date: 2014 Nov-Dec Impact factor: 5.166
Authors: Laia Mas-Expósito; Juan Antonio Amador-Campos; Juana Gómez-Benito; Lluís Lalucat-Jo Journal: Qual Life Res Date: 2011-02-03 Impact factor: 4.147