| Literature DB >> 15315852 |
David W C Beasley1, Li Li, Miguel T Suderman, Farshad Guirakhoo, Dennis W Trent, Thomas P Monath, Robert E Shope, Alan D T Barrett.
Abstract
The ability of antisera raised against a candidate Japanese encephalitis virus (JEV) vaccine, ChimeriVax-JE, and the currently licensed vaccine, JE-VAX, to protect against strains of JEV representing the four major genotypes was assessed. Neutralization assays and passive protection studies in mice showed that greatest protection was provided against strains of genotypes II and III, although some protection was also afforded against genotypes I and IV strains. ChimeriVax-JE stimulated protection that was comparable or superior to the JE-VAX control.Entities:
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Year: 2004 PMID: 15315852 DOI: 10.1016/j.vaccine.2004.03.027
Source DB: PubMed Journal: Vaccine ISSN: 0264-410X Impact factor: 3.641