Literature DB >> 15315754

Stem cells and cancer; the polycomb connection.

Merel E Valk-Lingbeek1, Sophia W M Bruggeman, Maarten van Lohuizen.   

Abstract

Proteins from the Polycomb group (PcG) are epigenetic chromatin modifiers involved in cancer development and also in the maintenance of embryonic and adult stem cells. The therapeutic potential of stem cells and the growing conviction that tumors contain stem cells highlights the importance of understanding the extrinsic and intrinsic circuitry controlling stem cell fate and their connections to cancer.

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Year:  2004        PMID： 15315754     DOI： 10.1016/j.cell.2004.08.005

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  272 in total

Review 1.  Identification of driver and passenger DNA methylation in cancer by epigenomic analysis.

Authors:  Satish Kalari; Gerd P Pfeifer
Journal:  Adv Genet       Date:  2010       Impact factor: 1.944

2.  DLK1, delta-like 1 homolog (Drosophila), regulates tumor cell differentiation in vivo.

Authors:  Asma Begum; Yuri Kim; Qun Lin; Zhong Yun
Journal:  Cancer Lett       Date:  2011-12-03       Impact factor: 8.679

Review 3.  The biology of head and neck cancer stem cells.

Authors:  Zhaocheng Zhang; Manoel Sant'Ana Filho; Jacques E Nör
Journal:  Oral Oncol       Date:  2011-11-08       Impact factor: 5.337

4.  Enzymatic assays for assessing histone deubiquitylation activity.

Authors:  Robyn T Sussman; Xiao-Yong Zhang; Steven B McMahon
Journal:  Methods       Date:  2011-04-12       Impact factor: 3.608

5.  Polycomb function during oogenesis is required for mouse embryonic development.

Authors:  Eszter Posfai; Rico Kunzmann; Vincent Brochard; Juliette Salvaing; Erik Cabuy; Tim C Roloff; Zichuan Liu; Mathieu Tardat; Maarten van Lohuizen; Miguel Vidal; Nathalie Beaujean; Antoine H F M Peters
Journal:  Genes Dev       Date:  2012-04-12       Impact factor: 11.361

Review 6.  Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer.

Authors:  Martin Sauvageau; Guy Sauvageau
Journal:  Cell Stem Cell       Date:  2010-09-03       Impact factor: 24.633

7.  Dynamic regulatory interactions of Polycomb group genes: MEDEA autoregulation is required for imprinted gene expression in Arabidopsis.

Authors:  Célia Baroux; Valeria Gagliardini; Damian R Page; Ueli Grossniklaus
Journal:  Genes Dev       Date:  2006-05-01       Impact factor: 11.361

Review 8.  Epigenomics and breast cancer.

Authors:  Pang-Kuo Lo; Saraswati Sukumar
Journal:  Pharmacogenomics       Date:  2008-12       Impact factor: 2.533

9.  250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies.

Authors:  Andrew J Dunbar; Lukasz P Gondek; Christine L O'Keefe; Hideki Makishima; Manjot S Rataul; Hadrian Szpurka; Mikkael A Sekeres; Xiao Fei Wang; Michael A McDevitt; Jaroslaw P Maciejewski
Journal:  Cancer Res       Date:  2008-12-15       Impact factor: 12.701

10.  Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus.

Authors:  Yan Liu; Fan Liu; Hao Yu; Xinyang Zhao; Goro Sashida; Anthony Deblasio; Michael Harr; Qing-Bai She; Zhenbang Chen; Hui-Kuan Lin; Silvana Di Giandomenico; Shannon E Elf; Youyang Yang; Yasuhiko Miyata; Gang Huang; Silvia Menendez; Ingo K Mellinghoff; Neal Rosen; Pier Paolo Pandolfi; Cyrus V Hedvat; Stephen D Nimer
Journal:  Sci Signal       Date:  2012-10-23       Impact factor: 8.192
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