| Literature DB >> 15308457 |
S Joanna Cowell1, David E Newby, Nicholas A Boon, Andrew T Elder.
Abstract
Calcific aortic stenosis is the commonest adult valvular heart condition seen in the western world. Its prevalence is continuing to rise, with predominance in older patients who are frequently undergoing successful aortic valve replacement. This review discusses the natural history of calcific aortic stenosis, highlights recent insights into its pathogenesis, and outlines current medical and surgical management. The potential role of novel therapeutic interventional strategies is discussed.Entities:
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Year: 2004 PMID: 15308457 DOI: 10.1093/ageing/afh175
Source DB: PubMed Journal: Age Ageing ISSN: 0002-0729 Impact factor: 10.668