Literature DB >> 15308279

Macrolides and ketolides: azithromycin, clarithromycin, telithromycin.

Jerry M Zuckerman1.   

Abstract

The advanced macrolides, azithromycin and clarithromycin, and the ketolide telithromycin are structural analogues of erythromycin. They have several distinct advantages when compared with erythromycin including enhanced spectrum of activity, more favorable pharmacokinetics and pharmacodynamics, once daily administration, and improved tolerability. This article reviews the pharmacokinetics, antimicrobial activity, clinical use, and adverse effects of these antimicrobial agents.

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Year:  2004        PMID: 15308279     DOI: 10.1016/j.idc.2004.04.010

Source DB:  PubMed          Journal:  Infect Dis Clin North Am        ISSN: 0891-5520            Impact factor:   5.982


  34 in total

1.  High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae.

Authors:  Nicole Wolter; Anthony M Smith; Donald E Low; Keith P Klugman
Journal:  Antimicrob Agents Chemother       Date:  2007-01-08       Impact factor: 5.191

2.  PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics.

Authors:  Alison E Fohner; Alex Sparreboom; Russ B Altman; Teri E Klein
Journal:  Pharmacogenet Genomics       Date:  2017-04       Impact factor: 2.089

Review 3.  Novel approaches to developing new antibiotics for bacterial infections.

Authors:  A R M Coates; Y Hu
Journal:  Br J Pharmacol       Date:  2007-08-20       Impact factor: 8.739

4.  Adverse events after mass azithromycin treatments for trachoma in Ethiopia.

Authors:  Berhan Ayele; Teshome Gebre; Jenafir I House; Zhaoxia Zhou; Charles E McCulloch; Travis C Porco; Bruce D Gaynor; Paul M Emerson; Thomas M Lietman; Jeremy D Keenan
Journal:  Am J Trop Med Hyg       Date:  2011-08       Impact factor: 2.345

5.  Usefulness of targeting lymphocyte Kv1.3-channels in the treatment of respiratory diseases.

Authors:  Itsuro Kazama; Tsutomu Tamada; Masahiro Tachi
Journal:  Inflamm Res       Date:  2015-07-24       Impact factor: 4.575

Review 6.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

7.  A comparison of in vitro ADME properties and pharmacokinetics of azithromycin and selected 15-membered ring macrolides in rodents.

Authors:  Astrid Milić; Vlatka Bencetić Mihaljević; Jovica Ralić; Ana Bokulić; Danijela Nožinić; Branka Tavčar; Boris Mildner; Vesna Munić; Ivica Malnar; Jasna Padovan
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2013-10-10       Impact factor: 2.441

Review 8.  Physiological significance of delayed rectifier K(+) channels (Kv1.3) expressed in T lymphocytes and their pathological significance in chronic kidney disease.

Authors:  Itsuro Kazama
Journal:  J Physiol Sci       Date:  2014-08-06       Impact factor: 2.781

9.  Minimal inhibitory and mutant prevention concentrations of azithromycin, clarithromycin and erythromycin for clinical isolates of Streptococcus pneumoniae.

Authors:  Kelli Metzler; Karl Drlica; Joseph M Blondeau
Journal:  J Antimicrob Chemother       Date:  2012-11-20       Impact factor: 5.790

Review 10.  Is there a role for inhaled corticosteroids and macrolide therapy in bronchiectasis?

Authors:  Paul King
Journal:  Drugs       Date:  2007       Impact factor: 9.546

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