Literature DB >> 15307443

Rapid biocompatible micro device fabrication by micro electro-discharge machining.

M Murali1, S H Yeo.   

Abstract

Fabrication of a biocompatible micro device is predominantly done by silicon micromachining techniques. The lithographic and etching techniques require preparation and the use of masks which are time consuming and costly. Since bio research involves highly complex mechanisms, the modeling and simulation is difficult and experimental study is inevitable. To incorporate frequent design changes and to realize the hardware quickly, fabrication processes, complementary to the silicon micromachining techniques are required. In the present work the feasibility of using micro electro-discharge machining (EDM) for the fabrication of biocompatible microdevice has been studied. Micro channels with feature size as small as 25 microm are realized. The process is further improved by the introduction of ultrasonic vibration of the workpiece and the total time taken for the hardware realization is about 4 hours. The effects of ultrasonic vibration on the roughness of the spark eroded surface has been studied and reported. The potential of using micro EDM for making biocompatible devices for bio experiments is demonstrated and the surface finish achieved is well within the recommended Rz and Ra values of 3.4 and 0.4 microm respectively for biological studies like implant abutment.

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Year:  2004        PMID: 15307443     DOI: 10.1023/b:bmmd.0000013364.71148.51

Source DB:  PubMed          Journal:  Biomed Microdevices        ISSN: 1387-2176            Impact factor:   2.838


  4 in total

1.  Low-dose sirolimus-eluting hydroxyapatite coating on stents does not increase platelet activation and adhesion ex vivo.

Authors:  Carlos L Alviar; Armando Tellez; Michael Wang; Pamela Potts; Doug Smith; Manus Tsui; Wladyslaw Budzynski; Albert E Raizner; Neal S Kleiman; Eli I Lev; Juan F Granada; Greg L Kaluza
Journal:  J Thromb Thrombolysis       Date:  2012-07       Impact factor: 2.300

Review 2.  Recent advances in drug eluting stents.

Authors:  Amey S Puranik; Eileen R Dawson; Nicholas A Peppas
Journal:  Int J Pharm       Date:  2012-10-29       Impact factor: 5.875

3.  Novel Quick Cell Patterning Using Light-Responsive Gas-Generating Polymer and Fluorescence Microscope.

Authors:  Hidetaka Ueno; Yoshinori Akagi; Shohei Yamamura
Journal:  Micromachines (Basel)       Date:  2022-02-18       Impact factor: 2.891

4.  Increased efficiency of direct nanoimprinting on planar and curved bulk titanium through surface modification.

Authors:  Andrew I M Greer; Krishna Seunarine; Ali Z Khokhar; Ian Maclaren; Alistair S Brydone; David A J Moran; Nikolaj Gadegaard
Journal:  Microelectron Eng       Date:  2013-12       Impact factor: 2.523

  4 in total

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