Literature DB >> 15303263

Antimicrobial activities of hydrophobic 2-arylbenzofurans and an isoflavone against vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus.

Toshio Fukai1, Yukio Oku, Yoshio Hano, Sumio Terada.   

Abstract

Eight 2-arylbenzofurans and an isoflavone isolated from medicinal plants were tested for their antimicrobial activities against vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Among these compounds, six hydrophobic 2-arylbenzofurans (log P = 4.4-8.7) exhibited considerable antibacterial activity against five VRE strains(VanA-, VanB-, and VanC-phenotypes) (MICs = 3.13-6.25 microg/mL). Five compounds also showed antibacterial activity against ten MRSA strains (MIC80 = 3.13 microg/mL).

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Year:  2004        PMID： 15303263     DOI： 10.1055/s-2004-827196

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  7 in total

Review 1.  Mulberry Diels-Alder-type adducts: isolation, structure, bioactivity, and synthesis.

Authors:  Si-Yuan Luo; Jun-Yu Zhu; Ming-Feng Zou; Sheng Yin; Gui-Hua Tang
Journal:  Nat Prod Bioprospect       Date:  2022-09-02

2.  Bioactive Benzofuran Derivatives from Cortex Mori Radicis, and Their Neuroprotective and Analgesic Activities Mediated by mGluR₁.

Authors:  Ya-Nan Wang; Mao-Feng Liu; Wei-Zhen Hou; Rui-Ming Xu; Jie Gao; An-Qi Lu; Mei-Ping Xie; Lan Li; Jian-Jun Zhang; Ying Peng; Li-Li Ma; Xiao-Liang Wang; Jian-Gong Shi; Su-Juan Wang
Journal:  Molecules       Date:  2017-02-08       Impact factor: 4.411

3.  A Tri-O-Bridged Diels-Alder Adduct from Cortex Mori Radicis.

Authors:  An-Qi Lu; Ming-Hua Chen; Jie Gao; Lu Wang; Han-Yu Yang; Lan Li; Bo Zhang; Hao-Ke He; Su-Juan Wang
Journal:  Molecules       Date:  2018-01-09       Impact factor: 4.411

4.  Chalcomoracin prevents vitreous-induced activation of AKT and migration of retinal pigment epithelial cells.

Authors:  Haote Han; Yanhui Yang; Bing Liu; Jingkui Tian; Lijun Dong; Hui Qi; Wei Zhu; Jiantao Wang; Hetian Lei
Journal:  J Cell Mol Med       Date:  2021-08-25       Impact factor: 5.310

5.  Chalcomoracin is a potent anticancer agent acting through triggering Oxidative stress via a mitophagy- and paraptosis-dependent mechanism.

Authors:  Haote Han; Chih-Chien Chou; Ruyi Li; Jiangyun Liu; Lin Zhang; Wei Zhu; Jin Hu; Bingxian Yang; Jingkui Tian
Journal:  Sci Rep       Date:  2018-06-22       Impact factor: 4.379

6.  Structural Insight of New Butyrylcholinesterase Inhibitors Based on Benzylbenzofuran Scaffold.

Authors:  Giovanna L Delogu; Antonella Fais; Francesca Pintus; Chinmayi Goyal; Maria J Matos; Benedetta Era; Amit Kumar
Journal:  Pharmaceuticals (Basel)       Date:  2022-03-02

7.  Synthesis and biological evaluation of 2-arylbenzofuran derivatives as potential anti-Alzheimer's disease agents.

Authors:  Yinling Yun; Yuhang Miao; Xiaoya Sun; Jie Sun; Xiaojing Wang
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051
  7 in total

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