Literature DB >> 1529339

Cloning of the 62-kilodalton component of basic transcription factor BTF2.

L Fischer1, M Gerard, C Chalut, Y Lutz, S Humbert, M Kanno, P Chambon, J M Egly.   

Abstract

Cloning of the mammalian basic transcription factors serves as a major step in understanding the mechanism of transcription initiation. The 62-kilodalton component (p62) of one of these transcription factors, BTF2 was cloned and overexpressed. A monoclonal antibody to this polypeptide inhibited transcription in vitro. Immunoaffinity experiments demonstrated that the 62-kilodalton component is closely associated with the other polypeptides present in the BTF2 factor. Sequence similarity suggests that BTF2 may be the human counterpart of RNA polymerase II initiation factor b from yeast.

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Year:  1992        PMID： 1529339     DOI： 10.1126/science.1529339

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  38 in total

1.  Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions.

Authors:  Maria Kraakman-van der Zwet; Wilhelmina J I Overkamp; Rebecca E E van Lange; Jeroen Essers; Annemarie van Duijn-Goedhart; Ingrid Wiggers; Srividya Swaminathan; Paul P W van Buul; Abdellatif Errami; Raoul T L Tan; Nicolaas G J Jaspers; Shyam K Sharan; Roland Kanaar; Malgorzata Z Zdzienicka
Journal:  Mol Cell Biol       Date:  2002-01       Impact factor: 4.272

2.  Regulation of CDK7 substrate specificity by MAT1 and TFIIH.

Authors:  K Y Yankulov; D L Bentley
Journal:  EMBO J       Date:  1997-04-01       Impact factor: 11.598

3.  The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro.

Authors:  H Lu; R P Fisher; P Bailey; A J Levine
Journal:  Mol Cell Biol       Date:  1997-10       Impact factor: 4.272

4.  MCM proteins are associated with RNA polymerase II holoenzyme.

Authors:  K Yankulov; I Todorov; P Romanowski; D Licatalosi; K Cilli; S McCracken; R Laskey; D L Bentley
Journal:  Mol Cell Biol       Date:  1999-09       Impact factor: 4.272

5.  The cdk7-cyclin H-MAT1 complex associated with TFIIH is localized in coiled bodies.

Authors:  P Jordan; C Cunha; M Carmo-Fonseca
Journal:  Mol Biol Cell       Date:  1997-07       Impact factor: 4.138

6.  Novel mutations in the RAD3 and SSL1 genes perturb genome stability by stimulating recombination between short repeats in Saccharomyces cerevisiae.

Authors:  S Maines; M C Negritto; X Wu; G M Manthey; A M Bailis
Journal:  Genetics       Date:  1998-11       Impact factor: 4.562

7.  TFIIH-mediated nucleotide excision repair and initiation of mRNA transcription in an optimized cell-free DNA repair and RNA transcription assay.

Authors:  M S Satoh; P C Hanawalt
Journal:  Nucleic Acids Res       Date:  1996-09-15       Impact factor: 16.971

8.  XPC and human homologs of RAD23: intracellular localization and relationship to other nucleotide excision repair complexes.

Authors:  P J van der Spek; A Eker; S Rademakers; C Visser; K Sugasawa; C Masutani; F Hanaoka; D Bootsma; J H Hoeijmakers
Journal:  Nucleic Acids Res       Date:  1996-07-01       Impact factor: 16.971

9.  An interaction between the Tfb1 and Ssl1 subunits of yeast TFIIH correlates with DNA repair activity.

Authors:  P Matsui; J DePaulo; S Buratowski
Journal:  Nucleic Acids Res       Date:  1995-03-11       Impact factor: 16.971

10.  Mutational analysis of ERCC3, which is involved in DNA repair and transcription initiation: identification of domains essential for the DNA repair function.

Authors:  L Ma; A Westbroek; A G Jochemsen; G Weeda; A Bosch; D Bootsma; J H Hoeijmakers; A J van der Eb
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272
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