OBJECTIVES: To investigate the cross-sectional relationships among self-reported frequencies of symptomatic hyperglycemia and hypoglycemia, HbA1c, and symptoms in the Quality of Well-Being Self-Administered (QWB-SA), and to examine the associations among these measures of glycemia and health-utility scores. METHODS: The study group included 1522 patients with diabetes who attended University of Michigan Health System clinics. Published studies were reviewed to identify symptoms in the QWB-SA that might be associated with measures of glycemia. Linear-regression analyses were performed to evaluate the strength of the associations among the frequency of self-reported measures of glycemia, QWB-SA symptoms, and QWB-SA-derived health-utility scores. RESULTS: Frequency of hyperglycemic symptoms was associated with 3% of the variance in the QWB-SA-derived health-utility score in type-1 diabetes and with 5% of the variance in type-2 diabetes. Frequency of hypoglycemic symptoms was not associated with the QWB-SA-derived health-utility score in type-1 diabetes but was associated with 1% of the variance in type-2 diabetes. HbAlc levels were not significantly associated with QWB-SA-derived health-utility scores. After controlling for age, gender, and complications, frequency of hyperglycemic symptoms was significantly associated with QWB-SA-derived health-utility scores in type-1 and type-2 diabetes. CONCLUSIONS: Reported frequency of hyperglycemic symptoms is associated with symptoms included in the QWB-SA and with QWB-SA-derived health-utility scores. The QWB-SA may be an appropriate measure to assess the health burden of hyperglycemia.
OBJECTIVES: To investigate the cross-sectional relationships among self-reported frequencies of symptomatic hyperglycemia and hypoglycemia, HbA1c, and symptoms in the Quality of Well-Being Self-Administered (QWB-SA), and to examine the associations among these measures of glycemia and health-utility scores. METHODS: The study group included 1522 patients with diabetes who attended University of Michigan Health System clinics. Published studies were reviewed to identify symptoms in the QWB-SA that might be associated with measures of glycemia. Linear-regression analyses were performed to evaluate the strength of the associations among the frequency of self-reported measures of glycemia, QWB-SA symptoms, and QWB-SA-derived health-utility scores. RESULTS: Frequency of hyperglycemic symptoms was associated with 3% of the variance in the QWB-SA-derived health-utility score in type-1 diabetes and with 5% of the variance in type-2 diabetes. Frequency of hypoglycemic symptoms was not associated with the QWB-SA-derived health-utility score in type-1 diabetes but was associated with 1% of the variance in type-2 diabetes. HbAlc levels were not significantly associated with QWB-SA-derived health-utility scores. After controlling for age, gender, and complications, frequency of hyperglycemic symptoms was significantly associated with QWB-SA-derived health-utility scores in type-1 and type-2 diabetes. CONCLUSIONS: Reported frequency of hyperglycemic symptoms is associated with symptoms included in the QWB-SA and with QWB-SA-derived health-utility scores. The QWB-SA may be an appropriate measure to assess the health burden of hyperglycemia.
Authors: J Todd Coffey; Michael Brandle; Honghong Zhou; Deanna Marriott; Ray Burke; Bahman P Tabaei; Michael M Engelgau; Robert M Kaplan; William H Herman Journal: Diabetes Care Date: 2002-12 Impact factor: 19.112
Authors: M Weinberger; M S Kirkman; G P Samsa; P A Cowper; E A Shortliffe; D L Simel; J R Feussner Journal: Med Care Date: 1994-12 Impact factor: 2.983
Authors: Erik J Groessl; Robert M Kaplan; W Jack Rejeski; Jeffrey A Katula; Abby C King; Georita Frierson; Nancy W Glynn; Fang-Chi Hsu; Michael Walkup; Marco Pahor Journal: Am J Prev Med Date: 2007-09 Impact factor: 5.043
Authors: R Brett McQueen; Samuel L Ellis; David M Maahs; Heather D Anderson; Kavita V Nair; Anne M Libby; Jonathan D Campbell Journal: Patient Date: 2014 Impact factor: 3.883
Authors: Karen L Saban; Kevin T Stroupe; Fred B Bryant; Domenic J Reda; Margaret M Browning; Denise M Hynes Journal: Qual Life Res Date: 2008-09-13 Impact factor: 4.147
Authors: Fernando Alvarez-Guisasola; Donald D Yin; Gonzalo Nocea; Ying Qiu; Panagiotis Mavros Journal: Health Qual Life Outcomes Date: 2010-08-19 Impact factor: 3.186