| Literature DB >> 15281796 |
Kyung-Hoon Lee1, Manolis Matzapetakis, Soumya Mitra, E Neil G Marsh, Vincent L Pecoraro.
Abstract
Substitution of an alanine for leucine (shown in light blue) in the hydrophobic interior of designed three-stranded coiled coils allows for the control of metal ion coordination number and geometry. The influence of this perturbation by a noncoordinating residue can be monitored by the dramatic impact on the 113Cd NMR spectrum. The structural effect occurs even when the residue substitution is as much as 7 A from the metal binding site.Entities:
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Year: 2004 PMID： 15281796 DOI： 10.1021/ja048839s
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419