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Literature DB >> 1527547

Improvement of parkinsonian features correlate with high plasma levodopa values after broad bean (Vicia faba) consumption.

J M Rabey¹, Y Vered, H Shabtai, E Graff, A D Korczyn.

Abstract

Five healthy volunteers and six patients with Parkinson's disease (PD) ate 250 g cooked broad beans after 12 hours without treatment. During the next four hours a substantial clinical improvement was noted, three patients showed severe dyskinesias, and plasma levodopa concentrations rose.

Entities: Chemical Disease Species

Mesh：

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Year: 1992 PMID： 1527547 PMCID： PMC489215 DOI： 10.1136/jnnp.55.8.725

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

10 in total

1. Source and physiological significance of plasma 3,4-dihydroxyphenylalanine in the rat.

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Authors: C J Gibson; S M Deikel; S N Young; Y M Binik
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10. Phenylalanine absorption and metabolism in Parkinsonian patients.

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10 in total

19 in total

Review 1. Mechanisms for alternative treatments in Parkinson's disease: acupuncture, tai chi, and other treatments.

Authors: Bijan D Ghaffari; Benzi Kluger
Journal: Curr Neurol Neurosci Rep Date: 2014-06 Impact factor: 5.081

2. Simultaneous determination of levodopa and carbidopa from fava bean, green peas and green beans by high performance liquid gas chromatography.

Authors: Mohseni Mehran S M; Golshani B
Journal: J Clin Diagn Res Date: 2013-06-01

Improvement of parkinsonian features correlate with high plasma levodopa values after broad bean (Vicia faba) consumption.

1. Source and physiological significance of plasma 3,4-dihydroxyphenylalanine in the rat.

2. Hyperactivity of remaining dopaminergic neurones after partial destruction of the nigro-striatal dopaminergic system in the rat.

3. Critical analysis of the disability in Parkinson's disease.

4. Aromatic amino acids and modification of parkinsonism.

5. Phenylalanine hydroxylase activity in mammalian cells.

6. Metabolism of carbidopa (1-(-)-alpha-hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate), an aromatic amino acid decarboxylase inhibitor, in the rat, rhesus monkey, and man.

7. Tyrosine administration increases striatal dopamine release in rats with partial nigrostriatal lesions.

8. Dihydroxyphenylalanine in rat food containing wheat and oats.

9. Behavioural and biochemical effects of tryptophan, tyrosine and phenylalanine in mice.

10. Phenylalanine absorption and metabolism in Parkinsonian patients.

Review 1. Mechanisms for alternative treatments in Parkinson's disease: acupuncture, tai chi, and other treatments.

2. Simultaneous determination of levodopa and carbidopa from fava bean, green peas and green beans by high performance liquid gas chromatography.

3. Nutritional and antinutritional attributes of faba bean (Vicia faba L.) germplasms growing in Bihar, India.

Review 4. Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease.

5. An increase in renal dopamine does not stimulate natriuresis after fava bean ingestion.

6. Nutritional therapies in Parkinson's disease.

Review 7. Therapies for Parkinson's diseases: alternatives to current pharmacological interventions.

8. Mucuna pruriens in Parkinson's disease: a double blind clinical and pharmacological study.

9. Initiation of treatment in early PD (evidences based).

Review 10. Estrogenic Plants: to Prevent Neurodegeneration and Memory Loss and Other Symptoms in Women After Menopause.