Literature DB >> 15268749

Innate immunity in aging: impact on macrophage function.

Julie Plowden1, Mary Renshaw-Hoelscher, Carrie Engleman, Jacqueline Katz, Suryaprakash Sambhara.   

Abstract

Innate and adaptive immune functions decline with age, leading to increased susceptibility to infectious diseases and cancer, and reduced responses to preventive vaccination in the elderly population. Macrophages function as 'pathogen sensors' and play an important role in the initiation of inflammatory responses, elimination of pathogens, manipulation of the adaptive immune response and reparation of damaged tissue. In this paper, we review the literature addressing the impact of aging on the macrophage population.

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Year:  2004        PMID： 15268749     DOI： 10.1111/j.1474-9728.2004.00102.x

Source DB:  PubMed          Journal:  Aging Cell        ISSN： 1474-9718            Impact factor:   9.304


  124 in total

1.  Immunosenescence and Challenges of Vaccination against Influenza in the Aging Population.

Authors:  Adrian J Reber; Tatiana Chirkova; Jin Hyang Kim; Weiping Cao; Renata Biber; David K Shay; Suryaprakash Sambhara
Journal:  Aging Dis       Date:  2011-09-30       Impact factor: 6.745

Review 2.  Aging and immune function: molecular mechanisms to interventions.

Authors:  Subramaniam Ponnappan; Usha Ponnappan
Journal:  Antioxid Redox Signal       Date:  2011-01-08       Impact factor: 8.401

Review 3.  Cell Therapy Strategies to Combat Immunosenescence.

Authors:  Elizabeth C Stahl; Bryan N Brown
Journal:  Organogenesis       Date:  2015-11-20       Impact factor: 2.500

Review 4.  Elderly patients and inflammatory bowel disease.

Authors:  Danielle Nimmons; Jimmy K Limdi
Journal:  World J Gastrointest Pharmacol Ther       Date:  2016-02-06

Review 5.  Immunosenescence: emerging challenges for an ageing population.

Authors:  Danielle Aw; Alberto B Silva; Donald B Palmer
Journal:  Immunology       Date:  2007-02-15       Impact factor: 7.397

6.  Aging and estrogen: modulation of inflammatory responses after injury.

Authors:  Christian R Gomez; Timothy P Plackett; Elizabeth J Kovacs
Journal:  Exp Gerontol       Date:  2007-01-03       Impact factor: 4.032

7.  Specific messenger RNA expression for signal transduction molecules by lipopolysaccharide in intestinal macrophages.

Authors:  K Nakata; H Inagawa; T Nishizawa; C Kohchi; G-I Soma
Journal:  Clin Exp Immunol       Date:  2006-03       Impact factor: 4.330

8.  Immunization by influenza virus-like particles protects aged mice against lethal influenza virus challenge.

Authors:  Zhiyuan Wen; Ling Ye; Yulong Gao; Lei Pan; Ke Dong; Zhigao Bu; Richard W Compans; Chinglai Yang
Journal:  Antiviral Res       Date:  2009-09-20       Impact factor: 5.970

9.  Discrete Dynamical Modeling of Influenza Virus Infection Suggests Age-Dependent Differences in Immunity.

Authors:  Ericka Keef; Li Ang Zhang; David Swigon; Alisa Urbano; G Bard Ermentrout; Michael Matuszewski; Franklin R Toapanta; Ted M Ross; Robert S Parker; Gilles Clermont
Journal:  J Virol       Date:  2017-11-14       Impact factor: 5.103

Review 10.  Asthma Over the Age of 65: All's Well That Ends Well.

Authors:  Alan P Baptist; Paula J Busse
Journal:  J Allergy Clin Immunol Pract       Date:  2018 May - Jun
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