| Literature DB >> 15260984 |
Louis F Reichardt1, William C Mobley.
Abstract
NGF and NT-3 both signal through TrkA receptors on the axons of developing sympathetic neurons, but while NGF supports survival and differentiation, NT-3 does not. In this issue of Cell, the difference is explained as the ability of NGF, but not NT-3, to induce internalization and retrograde transport of activated TrkA.Entities:
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Year: 2004 PMID： 15260984 DOI： 10.1016/j.cell.2004.07.008
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582