Literature DB >> 152598

Abnormalities in growth of skin fibroblasts of patients with Huntington's disease.

D S Barkley, S Hardiwidjaja, J H Menkes.   

Abstract

Culture characteristics in a variety of media were determined in 18 skin fibroblast cultures from 8 subjects with Huntington's disease (HD) and 20 cultures from 10 control subjects. Skin fibroblasts from HD subjects consistently and reproducibly demonstrated maximal cell densities that were higher than control values. There was no significant difference in growth rates. The relationship of this phenomenon to the HD gene is unknown, as are its specificity and time of appearance in the course of the illness.

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Year:  1977        PMID： 152598     DOI： 10.1002/ana.410010505

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  10 in total

1.  Predictive tests in Huntington's chorea.

Authors: 
Journal:  Br Med J       Date:  1978-03-04

2.  Qualitative and quantitative study of the growth and cell surface properties of Huntington's disease fibroblasts and age-matched controls. Lack of significant differences.

Authors:  J J Cassiman; J Verlinden; R F Vlietinck; J Bellemans; F Van Leuven; J Deroover; F Baro; H Van den Berghe
Journal:  Hum Genet       Date:  1979       Impact factor: 4.132

Review 3.  The current state of research with peripheral tissues in Huntington disease.

Authors:  G C Beverstock
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

4.  Huntington's-chorea fibroblasts. Cellular protein glycosylation.

Authors:  W Y Hung; D E Mold; A Tourian
Journal:  Biochem J       Date:  1980-09-15       Impact factor: 3.857

5.  The ups and downs of Huntington disease research.

Authors:  D E Comings
Journal:  Am J Hum Genet       Date:  1981-03       Impact factor: 11.025

Review 6.  Huntington disease: genetics and epidemiology.

Authors:  P M Conneally
Journal:  Am J Hum Genet       Date:  1984-05       Impact factor: 11.025

7.  Huntington disease and Tourette syndrome. I. Electron spin resonance of bed ghosts.

Authors:  D E Comings; A Pekkala; J R Schuh; P C Kuo; S I Chan
Journal:  Am J Hum Genet       Date:  1981-03       Impact factor: 11.025

8.  Skin fibroblasts in Huntington disease.

Authors:  I E Goetz; E Roberts; J Warren
Journal:  Am J Hum Genet       Date:  1981-03       Impact factor: 11.025

Review 9.  Advances in Modeling Polyglutamine Diseases Using Genome Editing Tools.

Authors:  Marianna Karwacka; Marta Olejniczak
Journal:  Cells       Date:  2022-02-02       Impact factor: 6.600

10.  A patient-derived cellular model for Huntington's disease reveals phenotypes at clinically relevant CAG lengths.

Authors:  Claudia Lin-Kar Hung; Tamara Maiuri; Laura Erin Bowie; Ryan Gotesman; Susie Son; Mina Falcone; James Victor Giordano; Tammy Gillis; Virginia Mattis; Trevor Lau; Vickie Kwan; Vanessa Wheeler; Jonathan Schertzer; Karun Singh; Ray Truant
Journal:  Mol Biol Cell       Date:  2018-09-26       Impact factor: 4.138
  10 in total

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