OBJECTIVE: The purpose of this study was to determine the effect of follicular aspiration on the incidence of ovarian hyperstimulation syndrome (OHSS). DESIGN: A retrospective study was done on 219 IVF cycles that proceeded to follicular aspiration (group A) and they were compared with 189 cycles of ovulation induction for non-IVF cycles (group B). We compared the incidence of OHSS in regularly ovulating patients (subgroups A1 and B1) and anovulatory patients (subgroups A2 and B2) in both groups. SETTINGS: The study took place at The Egyptian IVF-ET Center. PARTICIPANTS: Participants were 319 infertility patients. INTERVENTION: Ovulation was induced and follicles were aspirated. MAIN OUTCOME MEASURES: The incidences of moderate and severe OHSS were the main outcome measures. RESULTS: The incidence of OHSS in group B was significantly higher than that in group A (P = 0.016). There was no significant difference in the incidence of OHSS between subgroup A1 and subgroup B1 or between subgroup A2 and subgroup B2. CONCLUSIONS: Follicular aspiration had no effect on the incidence of OHSS. In contrast, the higher incidence of OHSS in group B was related to the higher incidence of anovulatory infertility.
OBJECTIVE: The purpose of this study was to determine the effect of follicular aspiration on the incidence of ovarian hyperstimulation syndrome (OHSS). DESIGN: A retrospective study was done on 219 IVF cycles that proceeded to follicular aspiration (group A) and they were compared with 189 cycles of ovulation induction for non-IVF cycles (group B). We compared the incidence of OHSS in regularly ovulating patients (subgroups A1 and B1) and anovulatory patients (subgroups A2 and B2) in both groups. SETTINGS: The study took place at The Egyptian IVF-ET Center. PARTICIPANTS: Participants were 319 infertilitypatients. INTERVENTION: Ovulation was induced and follicles were aspirated. MAIN OUTCOME MEASURES: The incidences of moderate and severe OHSS were the main outcome measures. RESULTS: The incidence of OHSS in group B was significantly higher than that in group A (P = 0.016). There was no significant difference in the incidence of OHSS between subgroup A1 and subgroup B1 or between subgroup A2 and subgroup B2. CONCLUSIONS: Follicular aspiration had no effect on the incidence of OHSS. In contrast, the higher incidence of OHSS in group B was related to the higher incidence of anovulatory infertility.