Literature DB >> 15254212

The virion host shutoff protein of herpes simplex virus type 1 has RNA degradation activity in primary neurons.

Stephanie S Strand1, Tambryn K Vanheyningen, David A Leib.   

Abstract

The virion host shutoff protein (Vhs) of herpes simplex virus type 1 induces destabilization of mRNA following infection. Our study of primary neurons from CD-1 mice demonstrates that vhs is functional in neurons but that more Vhs is required to mediate RNA degradation in neurons than in other susceptible cells.

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Year:  2004        PMID： 15254212      PMCID： PMC446108          DOI： 10.1128/JVI.78.15.8400-8403.2004

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  13 in total

1.  RNase L activity does not contribute to host RNA degradation induced by herpes simplex virus infection.

Authors:  Tracy J Smith; Robert H Silverman; David A Leib
Journal:  J Gen Virol       Date:  2003-04       Impact factor: 3.891

2.  Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41.

Authors:  C A Smibert; D C Johnson; J R Smiley
Journal:  J Gen Virol       Date:  1992-02       Impact factor: 3.891

3.  Analysis of conserved domains of UL41 of herpes simplex virus type 1 in virion host shutoff and pathogenesis.

Authors:  L I Strelow; D A Leib
Journal:  J Virol       Date:  1996-08       Impact factor: 5.103

4.  Infection of sympathetic and sensory neurones with herpes simplex virus does not elicit a shut-off of cellular protein synthesis: implications for viral latency and herpes vectors.

Authors:  P F Nichol; J Y Chang; E M Johnson; P D Olivo
Journal:  Neurobiol Dis       Date:  1994-11       Impact factor: 5.996

5.  Herpes simplex virus virion host shutoff protein requires a mammalian factor for efficient in vitro endoribonuclease activity.

Authors:  P Lu; F E Jones; H A Saffran; J R Smiley
Journal:  J Virol       Date:  2001-02       Impact factor: 5.103

6.  Astrocytes and oligodendrocytes in dissociated cell culture of adult rat optic nerve.

Authors:  P G Kennedy; R P Lisak
Journal:  Neurosci Lett       Date:  1980-03       Impact factor: 3.046

7.  mRNA decay during herpesvirus infections: interaction between a putative viral nuclease and a cellular translation factor.

Authors:  P Feng; D N Everly; G S Read
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

8.  Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.

Authors:  Tracy J Smith; Lynda A Morrison; David A Leib
Journal:  J Virol       Date:  2002-03       Impact factor: 5.103

9.  Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis.

Authors:  L I Strelow; D A Leib
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

Review 10.  Gene delivery using herpes simplex virus vectors.

Authors:  Edward A Burton; David J Fink; Joseph C Glorioso
Journal:  DNA Cell Biol       Date:  2002-12       Impact factor: 3.311
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  7 in total

1.  The herpes simplex virus type 1 vhs-UL41 gene secures viral replication by temporarily evading apoptotic cellular response to infection: Vhs-UL41 activity might require interactions with elements of cellular mRNA degradation machinery.

Authors:  Ari Barzilai; Ifaat Zivony-Elbom; Ronit Sarid; Eran Noah; Niza Frenkel
Journal:  J Virol       Date:  2006-01       Impact factor: 5.103

2.  Phosphorylation of the VP16 transcriptional activator protein during herpes simplex virus infection and mutational analysis of putative phosphorylation sites.

Authors:  Søren Ottosen; Francisco J Herrera; James R Doroghazi; Angela Hull; Sheenu Mittal; William S Lane; Steven J Triezenberg
Journal:  Virology       Date:  2005-11-17       Impact factor: 3.616

3.  Frequent release of low amounts of herpes simplex virus from neurons: results of a mathematical model.

Authors:  Joshua T Schiffer; Laith Abu-Raddad; Karen E Mark; Jia Zhu; Stacy Selke; Amalia Magaret; Anna Wald; Lawrence Corey
Journal:  Sci Transl Med       Date:  2009-11-18       Impact factor: 17.956

4.  The virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells.

Authors:  Christopher R Cotter; Marie L Nguyen; Jacob S Yount; Carolina B López; John A Blaho; Thomas M Moran
Journal:  PLoS One       Date:  2010-02-18       Impact factor: 3.240

5.  Selective ablation of virion host shutoff protein RNase activity attenuates herpes simplex virus 2 in mice.

Authors:  Maria Korom; Kristine M Wylie; Lynda A Morrison
Journal:  J Virol       Date:  2008-01-30       Impact factor: 5.103

6.  Deletion of the Virion Host Shut-off Gene Enhances Neuronal-Selective Transgene Expression from an HSV Vector Lacking Functional IE Genes.

Authors:  Yoshitaka Miyagawa; Gianluca Verlengia; Bonnie Reinhart; Fang Han; Hiroaki Uchida; Silvia Zucchini; William F Goins; Michele Simonato; Justus B Cohen; Joseph C Glorioso
Journal:  Mol Ther Methods Clin Dev       Date:  2017-06-16       Impact factor: 6.698

7.  The ESCRT-Related ATPase Vps4 Is Modulated by Interferon during Herpes Simplex Virus 1 Infection.

Authors:  Jorge Ruben Cabrera; Richard Manivanh; Brian J North; David A Leib
Journal:  mBio       Date:  2019-03-05       Impact factor: 7.786
  7 in total

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