Literature DB >> 15253426

Investigation of doxorubicin resistance in MCF-7 breast cancer cells using shot-gun comparative proteomics with proteolytic 18O labeling.

Kristy J Brown1, Catherine Fenselau.   

Abstract

A shot-gun comparative proteomic investigation utilizing proteolytic 18O labeling has been carried out on a drug susceptible MCF-7 human breast cancer cell line and a related cell line that is resistant to doxorubicin. The proteolytic 18O labeling method has been further refined and optimized for application to a protein fraction stemming from the cytosol of the breast cancer cells. The comparative investigation revealed several proteins with altered expression levels in the doxorubicin resistant line. These altered proteins are considered for a possible role in doxorubicin resistance.

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Year:  2004        PMID： 15253426     DOI： 10.1021/pr0340835

Source DB:  PubMed          Journal:  J Proteome Res        ISSN： 1535-3893            Impact factor:   4.466


  11 in total

1.  Mass spectrometry reveals specific and global molecular transformations during viral infection.

Authors:  Eden P Go; William R Wikoff; Zhouxin Shen; Grace O'Maille; Hirotoshi Morita; Thomas P Conrads; Anders Nordstrom; Sunia A Trauger; Wilasinee Uritboonthai; David A Lucas; King C Chan; Timothy D Veenstra; Hanna Lewicki; Michael B Oldstone; Anette Schneemann; Gary Siuzdak
Journal:  J Proteome Res       Date:  2006-09       Impact factor: 4.466

2.  ZoomQuant: an application for the quantitation of stable isotope labeled peptides.

Authors:  Brian D Halligan; Ronit Y Slyper; Simon N Twigger; Wayne Hicks; Michael Olivier; Andrew S Greene
Journal:  J Am Soc Mass Spectrom       Date:  2005-01-13       Impact factor: 3.109

3.  An automated method for the analysis of stable isotope labeling data in proteomics.

Authors:  Xiang Zhang; Wade Hines; Jiri Adamec; John M Asara; Stephen Naylor; Fred E Regnier
Journal:  J Am Soc Mass Spectrom       Date:  2005-07       Impact factor: 3.109

Review 4.  A proteomic primer for the clinician.

Authors:  Yurong Guo; Zongming Fu; Jennifer E Van Eyk
Journal:  Proc Am Thorac Soc       Date:  2007-01

5.  Trypsin is the primary mechanism by which the (18)O isotopic label is lost in quantitative proteomic studies.

Authors:  Peggi M Angel; Ron Orlando
Journal:  Anal Biochem       Date:  2006-09-22       Impact factor: 3.365

6.  pH dependency of the carboxyl oxygen exchange reaction catalyzed by lysyl endopeptidase and trypsin.

Authors:  Dagmar Hajkova; K C Sekhar Rao; Masaru Miyagi
Journal:  J Proteome Res       Date:  2006-07       Impact factor: 4.466

7.  Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1.

Authors:  Ashraf G Madian; Jagadish Hindupur; John D Hulleman; Naomi Diaz-Maldonado; Vartika R Mishra; Emmanuel Guigard; Cyril M Kay; Jean-Christophe Rochet; Fred E Regnier
Journal:  Mol Cell Proteomics       Date:  2011-11-21       Impact factor: 5.911

8.  Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach.

Authors:  Wei-Jun Qian; Matthew E Monroe; Tao Liu; Jon M Jacobs; Gordon A Anderson; Yufeng Shen; Ronald J Moore; David J Anderson; Rui Zhang; Steve E Calvano; Stephen F Lowry; Wenzhong Xiao; Lyle L Moldawer; Ronald W Davis; Ronald G Tompkins; David G Camp; Richard D Smith
Journal:  Mol Cell Proteomics       Date:  2005-03-07       Impact factor: 5.911

Review 9.  Use of comparative proteomics to identify potential resistance mechanisms in cancer treatment.

Authors:  Jian-Ting Zhang; Yang Liu
Journal:  Cancer Treat Rev       Date:  2007-09-12       Impact factor: 12.111

10.  Comparative proteomic analysis of tolerance and adaptation of ethanologenic Saccharomyces cerevisiae to furfural, a lignocellulosic inhibitory compound.

Authors:  Feng-Ming Lin; Bin Qiao; Ying-Jin Yuan
Journal:  Appl Environ Microbiol       Date:  2009-04-10       Impact factor: 4.792
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