Literature DB >> 15244411

Microwave-assisted parallel synthesis of a 4,6-diamino-2,2-dimethyl-1,2-dihydro-1-phenyl-s-triazine library.

Hong-Kee Lee1, Tariq M Rana.   

Abstract

Microwave-assisted parallel synthesis of a library of 20 phenyl dihydrotriazines was successfully achieved and compared to an identical library generated by conventional parallel synthesis. Microwave synthesis dramatically decreased reaction times from an average of 22 h to 35 min, and compounds generated using microwave irradiation were purer. Isolated yields of all the compounds were comparable when the two methods were used.

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Year:  2004        PMID: 15244411     DOI: 10.1021/cc049950x

Source DB:  PubMed          Journal:  J Comb Chem        ISSN: 1520-4766


  2 in total

1.  Design and assembly of new nonviral RNAi delivery agents by microwave-assisted quaternization (MAQ) of tertiary amines.

Authors:  Animesh Ghosh; Koushik Mukherjee; Xinpeng Jiang; Ying Zhou; Joshua McCarroll; James Qu; Pamela M Swain; Huricha Baigude; Tariq M Rana
Journal:  Bioconjug Chem       Date:  2010-09-15       Impact factor: 4.774

Review 2.  Advances in microwave-assisted combinatorial chemistry without polymer-supported reagents.

Authors:  Rafael Martínez-Palou
Journal:  Mol Divers       Date:  2006-08-01       Impact factor: 2.943

  2 in total

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