Literature DB >> 15241597

Genetic pathways and new progression markers for prostate cancer defined by microsatellite allelotyping.

Rolf von Knobloch1, Lutz Konrad, Peter J Barth, Heidrun Brandt, Sebastian Wille, Axel Heidenreich, Roland Moll, Rainer Hofmann.   

Abstract

A prospective study was carried out on a large cohort of males undergoing radical retropubic prostatectomy in order to identify genetic marker regions significantly associated with tumor formation. By comprehensive allotyping of chromosomes known to be associated with prostate carcinogenesis, an algorithm could be formulated for the genetic pathway and a method of discrimination between aggressive and less aggressive forms could be identified.

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Year:  2004        PMID： 15241597     DOI： 10.1007/s00120-004-0611-9

Source DB:  PubMed          Journal:  Urologe A        ISSN： 0340-2592            Impact factor:   0.639


  6 in total

1.  Serum DNA and urine DNA alterations of urinary transitional cell bladder carcinoma detected by fluorescent microsatellite analysis.

Authors:  R von Knobloch; A Hegele; H Brandt; P Olbert; A Heidenreich; R Hofmann
Journal:  Int J Cancer       Date:  2001-10-01       Impact factor: 7.396

2.  Loss of heterozygosity at 13q14 and 13q21 in high grade, high stage prostate cancer.

Authors:  J T Dong; J C Boyd; H F Frierson
Journal:  Prostate       Date:  2001-11-01       Impact factor: 4.104

3.  Genetic pattern of prostate cancer progression.

Authors:  T Saric; Z Brkanac; D A Troyer; S S Padalecki; M Sarosdy; K Williams; L Abadesco; R J Leach; P O'Connell
Journal:  Int J Cancer       Date:  1999-04-12       Impact factor: 7.396

4.  Prognostic significance of allelic imbalance of chromosome arms 7q, 8p, 16q, and 18q in stage T3N0M0 prostate cancer.

Authors:  R Jenkins; S Takahashi; K DeLacey; E Bergstralh; M Lieber
Journal:  Genes Chromosomes Cancer       Date:  1998-02       Impact factor: 5.006

5.  High frequency of serum DNA alterations in renal cell carcinoma detected by fluorescent microsatellite analysis.

Authors:  Rolf von Knobloch; Axel Hegele; Heidrun Brandt; Zoltan Varga; Sebastian Wille; Tilman Kälble; Axel Heidenreich; Rainer Hofmann
Journal:  Int J Cancer       Date:  2002-04-20       Impact factor: 7.396

6.  Homozygous and frequent deletion of proximal 8p sequences in human prostate cancers: identification of a potential tumor suppressor gene site.

Authors:  M A Prasad; T M Trybus; K J Wojno; J A Macoska
Journal:  Genes Chromosomes Cancer       Date:  1998-11       Impact factor: 5.006
  6 in total

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