Literature DB >> 15237220

DNA methylation profiles of CpG islands for cellular differentiation and development in mammals.

K Shiota1.   

Abstract

DNA methylation has been implicated in mammalian development. Transcription units contain CpG islands, but expression of CpG island associated genes in normal tissues was not believed to be controlled by DNA methylation. There are, however, numerous CpG islands containing tissue-dependent and differentially methylated regions (T-DMR), which are potential methylation sites in normal cells and tissues. Genomic scanning which focused on T-DMRs in CpG islands revealed that the DNA methylation profile of each cell/tissue is more complicated than previously considered. Differentiation of cells is associated with both methylation and demethylation, which occur at multiple loci. The epigenetic system characterized by DNA methylation requires cells to memorize gene expression patterns, thus, standardizing cellular phenotypes. Copyright 2004 S. Karger AG, Basel

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Year:  2004        PMID： 15237220     DOI： 10.1159/000078205

Source DB:  PubMed          Journal:  Cytogenet Genome Res        ISSN： 1424-8581            Impact factor:   1.636


  48 in total

1.  Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression.

Authors:  Fei Song; Joseph F Smith; Makoto T Kimura; Arlene D Morrow; Tomoki Matsuyama; Hiroki Nagase; William A Held
Journal:  Proc Natl Acad Sci U S A       Date:  2005-02-22       Impact factor: 11.205

2.  CpG methylation at the USF-binding site is important for the liver-specific transcription of the chipmunk HP-27 gene.

Authors:  Gen Fujii; Yuki Nakamura; Daisuke Tsukamoto; Michihiko Ito; Tadayoshi Shiba; Nobuhiko Takamatsu
Journal:  Biochem J       Date:  2006-04-01       Impact factor: 3.857

Review 3.  Applying whole-genome studies of epigenetic regulation to study human disease.

Authors:  J D Lieb; S Beck; M L Bulyk; P Farnham; N Hattori; S Henikoff; X S Liu; K Okumura; K Shiota; T Ushijima; J M Greally
Journal:  Cytogenet Genome Res       Date:  2006       Impact factor: 1.636

4.  Generation of leukemia inhibitory factor and basic fibroblast growth factor-dependent induced pluripotent stem cells from canine adult somatic cells.

Authors:  Jiesi Luo; Steven T Suhr; Eun Ah Chang; Kai Wang; Pablo J Ross; Laura L Nelson; Patrick J Venta; Jason G Knott; Jose B Cibelli
Journal:  Stem Cells Dev       Date:  2011-06-15       Impact factor: 3.272

5.  Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver.

Authors:  Alayne L Brunner; David S Johnson; Si Wan Kim; Anton Valouev; Timothy E Reddy; Norma F Neff; Elizabeth Anton; Catherine Medina; Loan Nguyen; Eric Chiao; Chuba B Oyolu; Gary P Schroth; Devin M Absher; Julie C Baker; Richard M Myers
Journal:  Genome Res       Date:  2009-03-09       Impact factor: 9.043

Review 6.  Defining the momiome: Promiscuous information transfer by mobile mitochondria and the mitochondrial genome.

Authors:  Bhupendra Singh; Josephine S Modica-Napolitano; Keshav K Singh
Journal:  Semin Cancer Biol       Date:  2017-05-11       Impact factor: 15.707

Review 7.  Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology.

Authors:  Krithika Vaidyanathan; Sean Durning; Lance Wells
Journal:  Crit Rev Biochem Mol Biol       Date:  2014-02-14       Impact factor: 8.250

8.  Tissue specific differentially methylated regions (TDMR): Changes in DNA methylation during development.

Authors:  Fei Song; Saleh Mahmood; Srimoyee Ghosh; Ping Liang; Domminic J Smiraglia; Hiroki Nagase; William A Held
Journal:  Genomics       Date:  2008-11-13       Impact factor: 5.736

9.  Cytosine methylation profiling of cancer cell lines.

Authors:  Mathias Ehrich; Julia Turner; Peter Gibbs; Lara Lipton; Mara Giovanneti; Charles Cantor; Dirk van den Boom
Journal:  Proc Natl Acad Sci U S A       Date:  2008-03-19       Impact factor: 11.205

10.  Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context.

Authors:  Brock C Christensen; E Andres Houseman; Carmen J Marsit; Shichun Zheng; Margaret R Wrensch; Joseph L Wiemels; Heather H Nelson; Margaret R Karagas; James F Padbury; Raphael Bueno; David J Sugarbaker; Ru-Fang Yeh; John K Wiencke; Karl T Kelsey
Journal:  PLoS Genet       Date:  2009-08-14       Impact factor: 5.917
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