Literature DB >> 15234777

Anticarcinogenic activity of Withania somnifera Dunal against Dalton's ascitic lymphoma.

A J M Christina1, D Gladwin Joseph, M Packialakshmi, R Kothai, S Jerry Heison Robert, N Chidambaranathan, M Ramasamy.   

Abstract

The effect of ethanolic extract of the root of Withania somnifera Dunal (REWS) against Dalton's Ascitic Lymphoma has been evaluated in Swiss albino mice. A significant increase in the life span and a decrease in the cancer cell number and tumour weight were noted in the tumour-induced mice after treatment with REWS. The hematological parameters were also corrected by REWS in tumour-induced mice. These observations are suggestive of the protective effect of REWS in Dalton's Ascitic Lymphoma (DAL).

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Year:  2004        PMID: 15234777     DOI: 10.1016/j.jep.2004.04.004

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN: 0378-8741            Impact factor:   4.360


  14 in total

1.  Therapeutic effect of Withania somnifera on pristane-induced model of SLE.

Authors:  Ujla Minhas; Ranjana Minz; Prabir Das; Archana Bhatnagar
Journal:  Inflammopharmacology       Date:  2011-12-13       Impact factor: 4.473

2.  Regression of Dalton's lymphoma in vivo via decline in lactate dehydrogenase and induction of apoptosis by a ruthenium(II)-complex containing 4-carboxy N-ethylbenzamide as ligand.

Authors:  Raj K Koiri; Surendra K Trigun; Lallan Mishra; Kiran Pandey; Deobrat Dixit; Santosh K Dubey
Journal:  Invest New Drugs       Date:  2008-11-29       Impact factor: 3.850

3.  Chlorinated Withanolides from Withania somnifera.

Authors:  Xiaoqin Tong; Huaping Zhang; Barbara N Timmermann
Journal:  Phytochem Lett       Date:  2011-12       Impact factor: 1.679

Review 4.  Molecular targets and mechanisms of cancer prevention and treatment by withaferin a, a naturally occurring steroidal lactone.

Authors:  Avani R Vyas; Shivendra V Singh
Journal:  AAPS J       Date:  2013-09-18       Impact factor: 4.009

5.  Analysis of arsenic induced physiological and biochemical responses in a medicinal plant, Withania somnifera.

Authors:  Fauzia Siddiqui; P K Tandon; Sudhakar Srivastava
Journal:  Physiol Mol Biol Plants       Date:  2015-01-08

6.  Antioxidant and anticancer evaluation of Scindapsus officinalis (Roxb.) Schott fruits.

Authors:  Shaktikumar C Shivhare; Arjun O Patidar; K G Malviya; K K Shivhare-Malviya
Journal:  Ayu       Date:  2011-07

Review 7.  Phytochemicals and Biogenic Metallic Nanoparticles as Anticancer Agents.

Authors:  Pasupuleti Visweswara Rao; Devi Nallappan; Kondeti Madhavi; Shafiqur Rahman; Lim Jun Wei; Siew Hua Gan
Journal:  Oxid Med Cell Longev       Date:  2016-02-23       Impact factor: 6.543

8.  Effect of Withania somnifera Extracts on Some Selective Biochemical, Hematological, and Immunological Parameters in Guinea Pigs Experimental Infected with E. coli.

Authors:  Mohamed El-Sayed El-Boshy; Osama Mohamed Abdalla; Angy Risha; Fatma Moustafa
Journal:  ISRN Vet Sci       Date:  2013-03-31

9.  Traditional medicinal plant knowledge and use by local healers in Sekoru District, Jimma Zone, Southwestern Ethiopia.

Authors:  Haile Yineger; Delenasaw Yewhalaw
Journal:  J Ethnobiol Ethnomed       Date:  2007-06-04       Impact factor: 2.733

10.  Withania somnifera root extract inhibits mammary cancer metastasis and epithelial to mesenchymal transition.

Authors:  Zhen Yang; Anapatricia Garcia; Songli Xu; Doris R Powell; Paula M Vertino; Shivendra Singh; Adam I Marcus
Journal:  PLoS One       Date:  2013-09-12       Impact factor: 3.240

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