Literature DB >> 15232425

Incongruity versus instability in the etiology of posttraumatic arthritis.

Todd O McKinley1, M James Rudert, Daniel C Koos, Thomas D Brown.   

Abstract

The etiology of posttraumatic arthritis is understood poorly but it clearly has a pathomechanical component. Posttraumatic arthritis likely results from irreversible cartilage damage sustained at the time of injury and chronic cartilage overloading resulting from articular incongruity and instability. However, the relative importance of instability and incongruity is unknown. Clinical studies show that the hip, knee, and ankle tolerate incongruity differently. However, all three joints poorly tolerate instability. Basic mechanical studies have shown that static loading of articular surface incongruities have caused relatively modest increases in contact pressure. However, static testing poorly replicates normal viscoelastic properties of cartilage, which may mask important transient stress elevations that occur during motion. Static tests also ignore potential abnormal loads that may accumulate throughout a motion cycle. We review the clinical and basic scientific evidence linking incongruity and instability to posttraumatic arthritis. Preliminary data from a newly developed dynamic ankle testing device are presented. Dynamic testing allows measurement of transient contact loads and loading rates that occur through the entire motion cycle and it opens the door to measure mechanical abnormalities associated with instability.

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Year:  2004        PMID: 15232425     DOI: 10.1097/01.blo.0000131639.89143.26

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  21 in total

1.  A retrospective study of posterior malleolus fractures.

Authors:  Hai-lin Xu; Xuan Li; Dian-ying Zhang; Zhong-guo Fu; Tian-bing Wang; Pei-xun Zhang; Bao-guo Jiang; Hui-liang Shen; Gang Wang; Guang-lin Wang; Xin-bao Wu
Journal:  Int Orthop       Date:  2012-07-10       Impact factor: 3.075

2.  Functional and Radiological Outcome of Schatzker type V and VI Tibial Plateau Fracture Treatment with Dual Plates with Minimum 3 years follow-up: A Prospective Study.

Authors:  Neil Rohra; Harpreet Singh Suri; Kewal Gangrade
Journal:  J Clin Diagn Res       Date:  2016-05-01

3.  Physical validation of a patient-specific contact finite element model of the ankle.

Authors:  Donald D Anderson; Jane K Goldsworthy; Wendy Li; M James Rudert; Yuki Tochigi; Thomas D Brown
Journal:  J Biomech       Date:  2007-04-12       Impact factor: 2.712

4.  Acute articular fracture severity and chronic cartilage stress challenge as quantitative risk factors for post-traumatic osteoarthritis: illustrative cases.

Authors:  K Z Masrouha; D D Anderson; T P Thomas; L L Kuhl; T D Brown; J L Marsh
Journal:  Iowa Orthop J       Date:  2010

5.  The role of mechanical forces in the initiation and progression of osteoarthritis.

Authors:  Joseph A Buckwalter
Journal:  HSS J       Date:  2012-02-14

6.  Relationship between stress ankle radiographs and injured ligaments on MRI.

Authors:  Kyoung Min Lee; Chin Youb Chung; Soon-Sun Kwon; Myung Ki Chung; Sung Hun Won; Seung Yeol Lee; Moon Seok Park
Journal:  Skeletal Radiol       Date:  2013-08-17       Impact factor: 2.199

7.  Effect of age and cytoskeletal elements on the indentation-dependent mechanical properties of chondrocytes.

Authors:  Nadeen O Chahine; Craig Blanchette; Cynthia B Thomas; Jeffrey Lu; Dominik Haudenschild; Gabriela G Loots
Journal:  PLoS One       Date:  2013-04-16       Impact factor: 3.240

Review 8.  Posterior malleolar fractures of the ankle.

Authors:  J Bartoníček; S Rammelt; M Tuček; O Naňka
Journal:  Eur J Trauma Emerg Surg       Date:  2015-08-08       Impact factor: 3.693

9.  Complementary models reveal cellular responses to contact stresses that contribute to post-traumatic osteoarthritis.

Authors:  James A Martin; Donald D Anderson; Jessica E Goetz; Douglas Fredericks; Douglas R Pedersen; Bruce P Ayati; J Lawrence Marsh; Joseph A Buckwalter
Journal:  J Orthop Res       Date:  2016-08-26       Impact factor: 3.494

10.  Patient-specific finite element analysis of chronic contact stress exposure after intraarticular fracture of the tibial plafond.

Authors:  Wendy Li; Donald D Anderson; Jane K Goldsworthy; J Lawrence Marsh; Thomas D Brown
Journal:  J Orthop Res       Date:  2008-08       Impact factor: 3.494

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