Literature DB >> 15232378

Multidetector-row computed tomography angiography for planning intra-arterial chemotherapy pump placement in patients with colorectal metastases to the liver.

Dushyant V Sahani1, Saravanan K Krishnamurthy, Sanjeeva Kalva, James Cusack, Peter F Hahn, John Santilli, Sanjay Saini, Peter R Mueller.   

Abstract

PURPOSE: The purpose of this study was to evaluate the use of multidetector computed tomography (MDCT) in the preoperative arterial evaluation of patients scheduled to undergo intra-arterial chemotherapy pump placement.
METHODS: Computed tomography scans of 30 patients with hepatic malignancies who were imaged with multiphase MDCT angiography for intra-arterial chemotherapy pump placement were retrospectively analyzed. Dual-phase helical CT was performed, and the arterial phase images were processed to depict the arterial anatomy and to identify pertinent anomalies. All findings were compared and correlated with surgical findings or catheter angiography if surgery was contraindicated.
RESULTS: Arterial anomalies identified on CT angiography in 20 of 30 patients included a replaced right hepatic artery (RHA; n = 6) or left hepatic artery (LHA; n = 8), a replaced common hepatic artery (n = 1), an accessory RHA (n = 2) or LHA (n = 6), a replaced gastroduodenal artery (GDA; n = 2), an extrahepatic connection between the accessory RHA and the replaced RHA (n = 1), and a common origin composed of the GDA and RHA and LHA (n = 2). There were no additional arteries or anomalies identified by catheter angiography, when available, or during surgery. Only 1 variant, an accessory hepatic artery, was not located during surgery. In 2 patients, the surgical team decided that pump placement was not feasible because of overly complex anatomy as determined by CT angiography. Computed tomography angiography showed an overall sensitivity of 100% and specificity of 97%.
CONCLUSIONS: Multidetector computed tomography angiography is accurate for the preoperative evaluation of normal and aberrant hepatic vasculature in patients under consideration for intra-arterial chemotherapy pump placement. Axial images alone permit recognition of vascular anomalies, including complex anatomy. Nevertheless, 3-dimensional rendering is useful to evaluate complex vascular anatomy and does not require catheter angiographic confirmation. In addition to aiding in selecting patients ideal for pump placement, MDCT permits noninvasive planning of their surgical approach.

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Year:  2004        PMID: 15232378     DOI: 10.1097/00004728-200407000-00007

Source DB:  PubMed          Journal:  J Comput Assist Tomogr        ISSN: 0363-8715            Impact factor:   1.826


  5 in total

1.  Multidetector CT (64 Slices) of the liver: examination techniques.

Authors:  Andrea Laghi
Journal:  Eur Radiol       Date:  2006-09-29       Impact factor: 5.315

2.  Anatomic variations of the hepatic arteries in 250 patients studied with 64-row CT angiography.

Authors:  Carlo Nicola De Cecco; Riccardo Ferrari; Marco Rengo; Pasquale Paolantonio; Fabrizio Vecchietti; Andrea Laghi
Journal:  Eur Radiol       Date:  2009-05-27       Impact factor: 5.315

3.  Preoperative imaging for hepatic resection of colorectal cancer metastasis.

Authors:  Timothy L Frankel; Richard Kinh Gian; William R Jarnagin
Journal:  J Gastrointest Oncol       Date:  2012-03

Review 4.  Variations of the hepatobiliary vasculature including coexistence of accessory right hepatic artery with unusually arising double cystic arteries: case report and literature review.

Authors:  Michał Polguj; Michał Podgórski; Piotr Hogendorf; Mirosław Topol
Journal:  Anat Sci Int       Date:  2013-12-06       Impact factor: 1.741

5.  Multidetector-row computed tomography for evaluating the branching angle of the celiac artery: a descriptive study.

Authors:  Hiroyuki Tokue; Azusa Tokue; Yoshito Tsushima
Journal:  BMC Med Imaging       Date:  2012-12-21       Impact factor: 1.930

  5 in total

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