Literature DB >> 1522734

A numerical study of the shape of the surface separating flow into branches in microvascular bifurcations.

G Enden1, A S Popel.   

Abstract

The shape of the separating surface formed by the streamlines entering the branches of microvascular bifurcations plays a major role in determining the distribution of red blood cells and other blood constituents downstream from the bifurcation. Using the finite element method, we determined the shape of the surface through numerical solution of three dimensional Navier-Stokes equations for fluid flow at low Reynolds numbers in a T-type bifurcation of circular tubes. Calculations were done for a wide range of daughter branch to parent vessel diameter ratios and flow ratios. The effect of Reynolds number was also studied. Our numerical results are in good agreement with previously reported experimental data of Rong and Carr (Microvascular Research, Vol. 39, pp. 186-202, 1990). The numerical results of this study will be used to predict the concentration of blood constituents downstream from microvascular bifurcations providing that the inlet concentration profile is known.

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Year:  1992        PMID: 1522734     DOI: 10.1115/1.2891401

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  8 in total

1.  Cell trapping in Y-junction microchannels: A numerical study of the bifurcation angle effect in inertial microfluidics.

Authors:  Scott J Hymel; Hongzhi Lan; Hideki Fujioka; Damir B Khismatullin
Journal:  Phys Fluids (1994)       Date:  2019-08-09       Impact factor: 3.521

2.  Blood-plasma separation in Y-shaped bifurcating microfluidic channels: a dissipative particle dynamics simulation study.

Authors:  Xuejin Li; Aleksander S Popel; George Em Karniadakis
Journal:  Phys Biol       Date:  2012-04-04       Impact factor: 2.583

3.  Converging three-dimensional Stokes flow of two fluids in a T-type bifurcation.

Authors:  Joseph Ong; Giora Enden; Aleksander S Popel
Journal:  J Fluid Mech       Date:  1994-07-10       Impact factor: 3.627

4.  Microsphere skimming in the porcine coronary arteries: Implications for flow quantification.

Authors:  Matthew Sinclair; Jack Lee; Andreas Schuster; Amedeo Chiribiri; Jeroen van den Wijngaard; Pepijn van Horssen; Maria Siebes; Jos A E Spaan; Eike Nagel; Nicolas P Smith
Journal:  Microvasc Res       Date:  2015-05-09       Impact factor: 3.514

5.  Simulated two-dimensional red blood cell motion, deformation, and partitioning in microvessel bifurcations.

Authors:  Jared O Barber; Jonathan P Alberding; Juan M Restrepo; Timothy W Secomb
Journal:  Ann Biomed Eng       Date:  2008-08-07       Impact factor: 3.934

6.  Simulated Red Blood Cell Motion in Microvessel Bifurcations: Effects of Cell-Cell Interactions on Cell Partitioning.

Authors:  Jared O Barber; Juan M Restrepo; Timothy W Secomb
Journal:  Cardiovasc Eng Technol       Date:  2011-10-13       Impact factor: 2.495

7.  Inflow/Outflow Boundary Conditions for Particle-Based Blood Flow Simulations: Application to Arterial Bifurcations and Trees.

Authors:  Kirill Lykov; Xuejin Li; Huan Lei; Igor V Pivkin; George Em Karniadakis
Journal:  PLoS Comput Biol       Date:  2015-08-28       Impact factor: 4.475

8.  Compressed vessels bias red blood cell partitioning at bifurcations in a hematocrit-dependent manner: Implications in tumor blood flow.

Authors:  Romain Enjalbert; David Hardman; Timm Krüger; Miguel O Bernabeu
Journal:  Proc Natl Acad Sci U S A       Date:  2021-06-17       Impact factor: 11.205

  8 in total

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