Literature DB >> 15223448

Influence of esophageal carcinoma operations on gastroesophageal reflux.

Jian Hu1, Renyuan Li, Li Sun, Yiming Ni.   

Abstract

BACKGROUND: Gastroesophageal reflux occurs more easily after esophageal carcinoma operations. Our objective was to compare the influence of three kinds of esophageal carcinoma operations on reflux.
METHODS: From May 1999 to May 2002, esophageal carcinoma operations were performed on 30 consecutive patients through left thoracotomy, including 10 cases completed with supraaortic, ante-aortic gastroesophageal anastomosis, 10 cases with subaortic gastroesophageal anastomosis, and 10 cases with apicothoracic retro-aortic gastroesophageal anastomosis. A 24-hour esophageal pH was recorded for every patient 3 months after the operation.
RESULTS: The number of reflux episodes per 24 hours (No. of episodes), the number of reflux episodes greater than or equal to 5 minutes per 24 hours (No. > or = 5 min), the time in minutes of the longest reflux episode recorded (longest episode) and the cumulative time of the esophageal pH less than 4 (total time that pH < 4) are all beyond normal limits. The difference in number of episodes between supraaortic, ante-aortic, and subaortic gastroesophageal anastomosis groups is not significant; but the other indexes are higher in the supraaortic, ante-aortic anastomosis group with significance (p < 0.05). The difference in number of episodes between supraaortic, ante-aortic, and apicothoracic retro-aortic gastroesophageal anastomosis groups is not significant while the other indexes are much higher in the supraaortic, ante-aortic anastomosis group with significance (p < 0.05); the difference in number of episodes between apicothoracic retro-aortic and subaortic gastroesophageal anastomosis groups is not significant while the other indexes are lower in the apicothoracic retro-aortic anastomosis group with significance (p < 0.05).
CONCLUSIONS: Gastroesophageal reflux occurred after all three types of esophageal carcinoma operations. The reflux is less severe in the apicothoracic retro-aortic anastomosis group than in the other two groups. The esophageal carcinoma operation with apicothoracic retro-aortic gastroesophageal anastomosis has more advantages to alleviate postoperative gastroesophageal reflux.

Entities:  

Mesh:

Year:  2004        PMID: 15223448     DOI: 10.1016/j.athoracsur.2003.11.056

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  2 in total

1.  Prevention of anastomotic stricture with a purse-string suture technique on the gastric side during esophageal carcinoma operations: retrospective study of 463 consecutive cases.

Authors:  Chong Zhang; Min-Hua Yao; Tao Jin; Li Sun; Jian Hu; Yu-Xin Zha
Journal:  World J Surg       Date:  2008-06       Impact factor: 3.352

2.  Expression of p14(ARF), p15(INK4b), p16(INK4a) and skp2 increases during esophageal squamous cell cancer progression.

Authors:  Peng Bai; Xue Xiao; Juan Zou; Lin Cui; Tri M Bui Nguyen; Jinsong Liu; Jianguo Xiao; Bin Chang; Jin Wu; He Wang
Journal:  Exp Ther Med       Date:  2012-03-22       Impact factor: 2.447

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.