Literature DB >> 15220787

Preventive analgesia is associated with reduced pain disability 3 weeks but not 6 months after major gynecologic surgery by laparotomy.

Joel Katz1, Lorenzo Cohen.   

Abstract

BACKGROUND: Most studies of preemptive or preventive analgesia restrict outcomes to pain and analgesic consumption in the acute postoperative period. The potential longer-term effects on these and other domains of functioning have received little empirical attention. The purpose of this study was to follow up patients who had received general anesthesia plus epidural fentanyl and lidocaine before (group 1) or after (group 2) incision or general anesthesia plus a sham epidural (group 3).
METHODS: Patients were contacted approximately 3 weeks and 6 months after surgery. A follow-up pain questionnaire and the McGill Pain Questionnaire were administered by telephone. The Mental Health Inventory and Pain Disability Index were mailed to patients, completed, and mailed back.
RESULTS: One hundred thirty-one of the 141 patients (93%) were reached 3 weeks after surgery (n = 41, n = 48, and n = 42 in groups 1, 2, and 3, respectively), and 109 (77%) were reached at 6 months (n = 35, n = 37, and n = 37 in groups 1, 2, and 3, respectively). Multivariate analysis of covariance indicated that that even after controlling for age and presence or absence of preoperative pain, Pain Disability Index scores (mean +/- SD) at the first follow-up were significantly lower in group 1 (17.3 +/-12.8) and group 2 (18.1 +/-17.0) compared with group 3 (26.3 +/- 18.3). McGill Pain Questionnaire and Mental Health Inventory scores did not differ significantly among the groups. There were no significant differences at the 6-month follow-up.
CONCLUSION: The short-term beneficial effects of preventive epidural analgesia translated into less pain disability 3 weeks after surgery. Progress in understanding the processes involved in postsurgical recovery and the risk factors for chronic postsurgical pain would be aided by baseline and postsurgical measures of relevant psychological, emotional, and physical variables.

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Year:  2004        PMID: 15220787     DOI: 10.1097/00000542-200407000-00026

Source DB:  PubMed          Journal:  Anesthesiology        ISSN: 0003-3022            Impact factor:   7.892


  20 in total

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Authors:  Heiko Neuss; Martin Schomaker; Wieland Raue; Gerold Koplin; Oliver Haase
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2.  Risk factors for chronic pain following breast cancer surgery: a prospective study.

Authors:  Ellen L Poleshuck; Jennifer Katz; Carl H Andrus; Laura A Hogan; Beth F Jung; Dale I Kulick; Robert H Dworkin
Journal:  J Pain       Date:  2006-09       Impact factor: 5.820

Review 3.  [What can we learn from the Scott Reuben case? Scientific misconduct in anaesthesiology].

Authors:  H L Rittner; P Kranke; M Schäfer; N Roewer; A Brack
Journal:  Anaesthesist       Date:  2009-12       Impact factor: 1.041

Review 4.  Pharmacotherapy for the prevention of chronic pain after surgery in adults.

Authors:  Luis Enrique Chaparro; Shane A Smith; R Andrew Moore; Philip J Wiffen; Ian Gilron
Journal:  Cochrane Database Syst Rev       Date:  2013-07-24

5.  Impact of Perioperative Epidural Placement on Postdischarge Opioid Use in Patients Undergoing Abdominal Surgery.

Authors:  Karim S Ladha; Elisabetta Patorno; Jun Liu; Brian T Bateman
Journal:  Anesthesiology       Date:  2016-02       Impact factor: 7.892

Review 6.  Local anaesthetics and regional anaesthesia for preventing chronic pain after surgery.

Authors:  Michael H Andreae; Doerthe A Andreae
Journal:  Cochrane Database Syst Rev       Date:  2012-10-17

Review 7.  [Transition from acute to chronic postsurgical pain. Physiology, risk factors and prevention].

Authors:  H J Gerbershagen
Journal:  Schmerz       Date:  2013-02       Impact factor: 1.107

8.  Postoperative pain and systemic inflammatory stress response after preoperative analgesia with clonidine or levobupivacaine: a randomized controlled trial.

Authors:  Jasminka Persec; Zoran Persec; Ino Husedzinovic
Journal:  Wien Klin Wochenschr       Date:  2009       Impact factor: 1.704

Review 9.  Regional anaesthesia to prevent chronic pain after surgery: a Cochrane systematic review and meta-analysis.

Authors:  M H Andreae; D A Andreae
Journal:  Br J Anaesth       Date:  2013-06-28       Impact factor: 9.166

10.  Randomized trial of preemptive local analgesia in vaginal surgery.

Authors:  Jaime B Long; Rhonda J Eiland; Joseph G Hentz; Pamela A Mergens; Paul M Magtibay; Rosanne M C Kho; Javier F Magrina; Jeffrey L Cornella
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2008-10-02
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