| Literature DB >> 15219999 |
Mauro Togni1, Jon Lindquist, Annegret Gerber, Uwe Kölsch, Andrea Hamm-Baarke, Stefanie Kliche, Burkhart Schraven.
Abstract
Research within the last 10 years has provided compelling evidence that adaptor proteins regulate the major pathways of lymphocyte activation. Based upon their differential subcellular localization, transmembrane adaptors and cytosolic adaptors can be distinguished. Here we review some of the most recent findings about both types of adaptor proteins which have facilitated our understanding how immunoreceptors control lymphocyte activation and differentiation.Mesh：
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Year: 2004 PMID： 15219999 DOI： 10.1016/j.molimm.2004.04.009
Source DB: PubMed Journal: Mol Immunol ISSN： 0161-5890 Impact factor: 4.407