Literature DB >> 15215427

ArrayProspector: a web resource of functional associations inferred from microarray expression data.

Lars Juhl Jensen1, Julien Lagarde, Christian von Mering, Peer Bork.   

Abstract

DNA microarray experiments have provided vast amounts of data which can be used for inferring gene function. However, most methods for predicting functional associations between genes from expression data are not suited to simultaneous analysis of multiple datasets, and a comprehensive resource of coexpression-based predictions is currently lacking. Here, we present an interactive web resource of gene associations predicted by applying a novel algorithm to all expression data in the Stanford Microarray Database. The underlying pre-computed database currently contains more than 200 000 high-confidence gene associations in 12 different species sampled from a broad taxonomic range. The resource allows every association to be inspected visually and can be accessed at http://www.bork.embl.de/ArrayProspector.

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Year:  2004        PMID: 15215427      PMCID: PMC441545          DOI: 10.1093/nar/gkh407

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  8 in total

1.  Statistical modeling of large microarray data sets to identify stimulus-response profiles.

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3.  The Stanford Microarray Database: data access and quality assessment tools.

Authors:  Jeremy Gollub; Catherine A Ball; Gail Binkley; Janos Demeter; David B Finkelstein; Joan M Hebert; Tina Hernandez-Boussard; Heng Jin; Miroslava Kaloper; John C Matese; Mark Schroeder; Patrick O Brown; David Botstein; Gavin Sherlock
Journal:  Nucleic Acids Res       Date:  2003-01-01       Impact factor: 16.971

4.  STRING: a database of predicted functional associations between proteins.

Authors:  Christian von Mering; Martijn Huynen; Daniel Jaeggi; Steffen Schmidt; Peer Bork; Berend Snel
Journal:  Nucleic Acids Res       Date:  2003-01-01       Impact factor: 16.971

5.  A genome-wide transcriptional analysis of the mitotic cell cycle.

Authors:  R J Cho; M J Campbell; E A Winzeler; L Steinmetz; A Conway; L Wodicka; T G Wolfsberg; A E Gabrielian; D Landsman; D J Lockhart; R W Davis
Journal:  Mol Cell       Date:  1998-07       Impact factor: 17.970

6.  Cluster analysis and display of genome-wide expression patterns.

Authors:  M B Eisen; P T Spellman; P O Brown; D Botstein
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

7.  Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization.

Authors:  P T Spellman; G Sherlock; M Q Zhang; V R Iyer; K Anders; M B Eisen; P O Brown; D Botstein; B Futcher
Journal:  Mol Biol Cell       Date:  1998-12       Impact factor: 4.138

8.  A new non-linear normalization method for reducing variability in DNA microarray experiments.

Authors:  Christopher Workman; Lars Juhl Jensen; Hanne Jarmer; Randy Berka; Laurent Gautier; Henrik Bjørn Nielser; Hans-Henrik Saxild; Claus Nielsen; Søren Brunak; Steen Knudsen
Journal:  Genome Biol       Date:  2002-08-30       Impact factor: 13.583

  8 in total
  9 in total

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Journal:  Methods Enzymol       Date:  2007       Impact factor: 1.600

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Authors:  Irina M Armean; Kathryn S Lilley; Matthew W B Trotter
Journal:  Mol Cell Proteomics       Date:  2012-10-15       Impact factor: 5.911

3.  SPICi: a fast clustering algorithm for large biological networks.

Authors:  Peng Jiang; Mona Singh
Journal:  Bioinformatics       Date:  2010-02-24       Impact factor: 6.937

4.  Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network.

Authors:  Bolan Linghu; Evan S Snitkin; Zhenjun Hu; Yu Xia; Charles Delisi
Journal:  Genome Biol       Date:  2009-09-03       Impact factor: 13.583

5.  Generation and Analysis of Large-Scale Data-Driven Mycobacterium tuberculosis Functional Networks for Drug Target Identification.

Authors:  Gaston K Mazandu; Nicola J Mulder
Journal:  Adv Bioinformatics       Date:  2011-11-29

6.  cisRED: a database system for genome-scale computational discovery of regulatory elements.

Authors:  G Robertson; M Bilenky; K Lin; A He; W Yuen; M Dagpinar; R Varhol; K Teague; O L Griffith; X Zhang; Y Pan; M Hassel; M C Sleumer; W Pan; E D Pleasance; M Chuang; H Hao; Y Y Li; N Robertson; C Fjell; B Li; S B Montgomery; T Astakhova; J Zhou; J Sander; A S Siddiqui; S J M Jones
Journal:  Nucleic Acids Res       Date:  2006-01-01       Impact factor: 16.971

7.  Assessing systems properties of yeast mitochondria through an interaction map of the organelle.

Authors:  Fabiana Perocchi; Lars J Jensen; Julien Gagneur; Uwe Ahting; Christian von Mering; Peer Bork; Holger Prokisch; Lars M Steinmetz
Journal:  PLoS Genet       Date:  2006-10-20       Impact factor: 5.917

8.  STRING: known and predicted protein-protein associations, integrated and transferred across organisms.

Authors:  Christian von Mering; Lars J Jensen; Berend Snel; Sean D Hooper; Markus Krupp; Mathilde Foglierini; Nelly Jouffre; Martijn A Huynen; Peer Bork
Journal:  Nucleic Acids Res       Date:  2005-01-01       Impact factor: 16.971

9.  Exploration of the omics evidence landscape: adding qualitative labels to predicted protein-protein interactions.

Authors:  Vera van Noort; Berend Snel; Martijn A Huynen
Journal:  Genome Biol       Date:  2007       Impact factor: 13.583

  9 in total

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