Literature DB >> 15213797

Emerging Therapeutic Strategies for Treating Alzheimer's Disease in Primary Care.

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Abstract

This Academic Highlights section of The Primary Care Companion to The Journal of Clinical Psychiatry presents a report from "Global Challenges in Alzheimer's Disease: Emerging Therapeutic Strategies," a satellite symposium of the Eleventh Annual International Congress of the International Psychogeriatric Association held August 20, 2003, in Chicago, Ill. The symposium and this Academic Highlights were sponsored by an unrestricted educational grant from Forest Laboratories, Inc. The chair was George T. Grossberg, M.D., Department of Psychiatry, Department of Internal Medicine, St. Louis University Health Science Center and Wohl Clinic, St. Louis, Mo. The other faculty members were Jody Corey-Bloom, M.D., Ph.D., Department of Neurosciences, University of California, San Diego and Veteran's Affairs Medical Center, La Jolla, Calif.; Gary W. Small, M.D., Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, University of California, Los Angeles; and Pierre N. Tariot, M.D., Departments of Psychiatry, Medicine, and Neurology and the Center for Aging and Developmental Biology, University of Rochester Medical Center and Monroe Community Hospital, Rochester, N.Y.

Entities:  

Year:  2003        PMID: 15213797      PMCID: PMC419397     

Source DB:  PubMed          Journal:  Prim Care Companion J Clin Psychiatry        ISSN: 1523-5998


  23 in total

1.  N-Methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease.

Authors:  C Sze; H Bi; B K Kleinschmidt-DeMasters; C M Filley; L J Martin
Journal:  J Neurol Sci       Date:  2001-01-01       Impact factor: 3.181

2.  An inventory to assess activities of daily living for clinical trials in Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

Authors:  D Galasko; D Bennett; M Sano; C Ernesto; R Thomas; M Grundman; S Ferris
Journal:  Alzheimer Dis Assoc Disord       Date:  1997       Impact factor: 2.703

3.  The impact of metrifonate therapy on caregivers of patients with Alzheimer's disease: results from the MALT clinical trial. Metrifonate in Alzheimer's Disease Trial.

Authors:  R Shikiar; A Shakespeare; P P Sagnier; D Wilkinson; I McKeith; J F Dartigues; B Dubois
Journal:  J Am Geriatr Soc       Date:  2000-03       Impact factor: 5.562

4.  Neuroprotective and symptomatological action of memantine relevant for Alzheimer's disease--a unified glutamatergic hypothesis on the mechanism of action.

Authors:  W Danysz; C G Parsons; H J Mobius; A Stoffler; G Quack
Journal:  Neurotox Res       Date:  2000       Impact factor: 3.911

5.  Long-term tacrine (Cognex) treatment: effects on nursing home placement and mortality, Tacrine Study Group.

Authors:  D Knopman; L Schneider; K Davis; S Talwalker; F Smith; T Hoover; S Gracon
Journal:  Neurology       Date:  1996-07       Impact factor: 9.910

6.  Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease.

Authors:  G W Small; L M Ercoli; D H Silverman; S C Huang; S Komo; S Y Bookheimer; H Lavretsky; K Miller; P Siddarth; N L Rasgon; J C Mazziotta; S Saxena; H M Wu; M S Mega; J L Cummings; A M Saunders; M A Pericak-Vance; A D Roses; J R Barrio; M E Phelps
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

Review 7.  Evaluation of memantine for neuroprotection in dementia.

Authors:  K K Jain
Journal:  Expert Opin Investig Drugs       Date:  2000-06       Impact factor: 6.206

8.  Excitotoxicity-induced expression of amyloid precursor protein (beta-APP) in the hippocampus and cortex of rat brain. an electron-microscopy and biochemical study.

Authors:  W Gordon-Krajcer; B Gajkowska
Journal:  Folia Neuropathol       Date:  2001       Impact factor: 2.038

9.  The impact of symptom severity on the cost of Alzheimer's disease.

Authors:  Gary W Small; Diana D McDonnell; Rachelle L Brooks; George Papadopoulos
Journal:  J Am Geriatr Soc       Date:  2002-02       Impact factor: 5.562

10.  Early and widespread cholinergic losses differentiate dementia with Lewy bodies from Alzheimer disease.

Authors:  Pietro Tiraboschi; Larry A Hansen; Michael Alford; Annette Merdes; Eliezer Masliah; Leon J Thal; Jody Corey-Bloom
Journal:  Arch Gen Psychiatry       Date:  2002-10
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