AIMS: To examine the predictive value of early developmental testing for identifying neuromotor and perceptual-motor impairment at school age in children with neonatal encephalopathy (NE). METHODS: Eighty full term infants with NE were followed longitudinally. Where possible, children were tested on the Griffiths scales at 1 and 2 years and at 5-6 years, on the Touwen Examination, Movement ABC, and WPPSI. The relation between the Griffiths scores and later outcome measures was examined using correlation coefficients and sensitivity and specificity values. RESULTS: By 2 years, 25 children with cerebral palsy were too severely impaired to be formally assessed and remained so at 5-6 years. Abnormal Griffiths scores were obtained by 12% and 7% of the children at 1 and 2 years respectively. At 5-6 years, 33% had poor Movement ABC scores and 15% poor WPPSI scores. The highest correlation between Griffiths scores and the outcome measures was for the Movement ABC (0.72), although this accounted for only 50% of the variance. Sensitivity scores for the Movement ABC were below 70% but specificity was 100%. CONCLUSIONS: A poor score on the Griffiths scales at 1 and/or 2 years is a good predictor of impairment at school age. However, a normal score in the early years cannot preclude later neurological, perceptual-motor, or cognitive abnormalities.
AIMS: To examine the predictive value of early developmental testing for identifying neuromotor and perceptual-motor impairment at school age in children with neonatal encephalopathy (NE). METHODS: Eighty full term infants with NE were followed longitudinally. Where possible, children were tested on the Griffiths scales at 1 and 2 years and at 5-6 years, on the Touwen Examination, Movement ABC, and WPPSI. The relation between the Griffiths scores and later outcome measures was examined using correlation coefficients and sensitivity and specificity values. RESULTS: By 2 years, 25 children with cerebral palsy were too severely impaired to be formally assessed and remained so at 5-6 years. Abnormal Griffiths scores were obtained by 12% and 7% of the children at 1 and 2 years respectively. At 5-6 years, 33% had poor Movement ABC scores and 15% poor WPPSI scores. The highest correlation between Griffiths scores and the outcome measures was for the Movement ABC (0.72), although this accounted for only 50% of the variance. Sensitivity scores for the Movement ABC were below 70% but specificity was 100%. CONCLUSIONS: A poor score on the Griffiths scales at 1 and/or 2 years is a good predictor of impairment at school age. However, a normal score in the early years cannot preclude later neurological, perceptual-motor, or cognitive abnormalities.
Authors: L G M van Rooij; M C Toet; D Osredkar; A C van Huffelen; F Groenendaal; L S de Vries Journal: Arch Dis Child Fetal Neonatal Ed Date: 2005-05 Impact factor: 5.747
Authors: Athina Pappas; Seetha Shankaran; Scott A McDonald; Betty R Vohr; Susan R Hintz; Richard A Ehrenkranz; Jon E Tyson; Kimberly Yolton; Abhik Das; Rebecca Bara; Jane Hammond; Rosemary D Higgins Journal: Pediatrics Date: 2015-03 Impact factor: 7.124
Authors: Alessandro Crippa; Christian Salvatore; Paolo Perego; Sara Forti; Maria Nobile; Massimo Molteni; Isabella Castiglioni Journal: J Autism Dev Disord Date: 2015-07
Authors: A David Edwards; Peter Brocklehurst; Alistair J Gunn; Henry Halliday; Edmund Juszczak; Malcolm Levene; Brenda Strohm; Marianne Thoresen; Andrew Whitelaw; Denis Azzopardi Journal: BMJ Date: 2010-02-09
Authors: Jennifer K Forsyth; Lauren M Ellman; Antti Tanskanen; Ulla Mustonen; Matti O Huttunen; Jaana Suvisaari; Tyrone D Cannon Journal: Schizophr Bull Date: 2012-09-01 Impact factor: 9.306
Authors: Montasser Nadeem; Deirdre M Murray; Geraldine B Boylan; Eugene M Dempsey; Cornelius A Ryan Journal: BMC Pediatr Date: 2011-02-04 Impact factor: 2.125