Literature DB >> 15209168

Pyridazines. Part 37: Facile solution phase combinatorial synthesis of highly substituted pyridazin-3-ones.

Eddy Sotelo1.   

Abstract

Arrays of polysubstituted pyridazinones were prepared through three- or four-component transformations starting from the readily accessible ene-adducts 2.

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Year:  2004        PMID： 15209168     DOI： 10.1023/b:modi.0000025628.01102.81

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  4 in total

1.  A Novel Concept in Combinatorial Chemistry in Solution with the Advantages of Solid-Phase Synthesis: Formation of N-Betaines by Multicomponent Domino Reactions This work was supported as part of the BMBF Project "Kombinatorische Chemie" (grant number 03 D0056 2). We thank BASF AG, Ludwigshafen, and the Fonds der Chemischen Industrie for generous support.

Authors:  Lutz F. Tietze; Holger Evers; Enno Töpken
Journal:  Angew Chem Int Ed Engl       Date:  2001-03-02       Impact factor: 15.336

Review 2.  Pharmacologically active pyridazine derivatives. Part 1.

Authors:  G Heinisch; H Frank
Journal:  Prog Med Chem       Date:  1990

3.  Pyridazines. XIII. Synthesis of 6-aryl-5-oxygenated substituted-3(2H)-pyridazinones and evaluation as platelet aggregation inhibitors.

Authors:  R Laguna; B Rodriguez-Liñares; E Cano; I Estevez; E Raviña; E Sotelo
Journal:  Chem Pharm Bull (Tokyo)       Date:  1997-07       Impact factor: 1.645

4.  Pyridazinones as selective cyclooxygenase-2 inhibitors.

Authors:  Chun Sing Li; Christine Brideau; Chi Chung Chan; Chantal Savoie; David Claveau; Stella Charleson; Robert Gordon; Gillian Greig; Jacques Yves Gauthier; Cheuk K Lau; Denis Riendeau; Michel Thérien; Elizabeth Wong; Petpiboon Prasit
Journal:  Bioorg Med Chem Lett       Date:  2003-02-24       Impact factor: 2.823
  4 in total

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