| Literature DB >> 15203032 |
Mei Zhang1, Grant A Moore, Sharon J Gardiner, Evan J Begg.
Abstract
A rapid and simple HPLC assay was developed for the determination of rofecoxib in human plasma and breast milk. After solid-phase extraction, rofecoxib was resolved on a C18 column and detected by UV detection at 272 nm. Standard curves were linear over the concentration range 10-2000 microg/L (r2 >0.99). Intra- and inter-day coefficients of variation for both matrices were <10% and the limit of quantification was around 10 microg/L.Entities:
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Year: 2004 PMID： 15203032 DOI： 10.1016/j.jchromb.2004.04.011
Source DB: PubMed Journal: J Chromatogr B Analyt Technol Biomed Life Sci ISSN： 1570-0232 Impact factor: 3.205