Literature DB >> 15201189

BioSilico: an integrated metabolic database system.

Bo Kyeng Hou1, Jin Sik Kim, Ji Hoon Jun, Dong-Yup Lee, Yong Wook Kim, Sujin Chae, Mira Roh, Yong-Ho In, Sang Yup Lee.   

Abstract

BioSilico is a web-based database system that facilitates the search and analysis of metabolic pathways. Heterogeneous metabolic databases including LIGAND, ENZYME, EcoCyc and MetaCyc are integrated in a systematic way, thereby allowing users to efficiently retrieve the relevant information on enzymes, biochemical compounds and reactions. In addition, it provides well-designed view pages for more detailed summary information. BioSilico is developed as an extensible system with a robust systematic architecture.

Mesh:

Year:  2004        PMID: 15201189     DOI: 10.1093/bioinformatics/bth363

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  12 in total

1.  VimA-dependent modulation of acetyl coenzyme A levels and lipid A biosynthesis can alter virulence in Porphyromonas gingivalis.

Authors:  A Wilson Aruni; J Lee; D Osbourne; Y Dou; F Roy; A Muthiah; D S Boskovic; H M Fletcher
Journal:  Infect Immun       Date:  2011-12-05       Impact factor: 3.441

2.  Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene knockout simulation.

Authors:  Sang Jun Lee; Dong-Yup Lee; Tae Yong Kim; Byung Hun Kim; Jinwon Lee; Sang Yup Lee
Journal:  Appl Environ Microbiol       Date:  2005-12       Impact factor: 4.792

3.  Genome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast Pichia pastoris for strain improvement.

Authors:  Bevan Ks Chung; Suresh Selvarasu; Camattari Andrea; Jimyoung Ryu; Hyeokweon Lee; Jungoh Ahn; Hongweon Lee; Dong-Yup Lee
Journal:  Microb Cell Fact       Date:  2010-07-01       Impact factor: 5.328

4.  Metabolome variations in the Porphyromonas gingivalis vimA mutant during hydrogen peroxide-induced oxidative stress.

Authors:  R M E McKenzie; W Aruni; N A Johnson; A Robles; Y Dou; L Henry; D S Boskovic; H M Fletcher
Journal:  Mol Oral Microbiol       Date:  2014-10-16       Impact factor: 3.563

5.  Genome-based metabolic engineering of Mannheimia succiniciproducens for succinic acid production.

Authors:  Sang Jun Lee; Hyohak Song; Sang Yup Lee
Journal:  Appl Environ Microbiol       Date:  2006-03       Impact factor: 4.792

6.  Metabolite essentiality elucidates robustness of Escherichia coli metabolism.

Authors:  Pan-Jun Kim; Dong-Yup Lee; Tae Yong Kim; Kwang Ho Lee; Hawoong Jeong; Sang Yup Lee; Sunwon Park
Journal:  Proc Natl Acad Sci U S A       Date:  2007-08-13       Impact factor: 11.205

7.  Involvement of PG2212 zinc finger protein in the regulation of oxidative stress resistance in Porphyromonas gingivalis W83.

Authors:  Yuetan Dou; Wilson Aruni; Tianlong Luo; Francis Roy; Charles Wang; Hansel M Fletcher
Journal:  J Bacteriol       Date:  2014-09-15       Impact factor: 3.490

8.  The genome-scale metabolic network analysis of Zymomonas mobilis ZM4 explains physiological features and suggests ethanol and succinic acid production strategies.

Authors:  Kyung Yun Lee; Jong Myoung Park; Tae Yong Kim; Hongseok Yun; Sang Yup Lee
Journal:  Microb Cell Fact       Date:  2010-11-24       Impact factor: 5.328

9.  BKM-react, an integrated biochemical reaction database.

Authors:  Maren Lang; Michael Stelzer; Dietmar Schomburg
Journal:  BMC Biochem       Date:  2011-08-08       Impact factor: 4.059

10.  Genome-scale reconstruction and in silico analysis of the Ralstonia eutropha H16 for polyhydroxyalkanoate synthesis, lithoautotrophic growth, and 2-methyl citric acid production.

Authors:  Jong Myoung Park; Tae Yong Kim; Sang Yup Lee
Journal:  BMC Syst Biol       Date:  2011-06-28
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