Literature DB >> 1519268

Sterol molecule: structure, biosynthesis, and function.

K Bloch1.   

Abstract

This review briefly summarizes key researches on the structure of the sterol molecule from its very beginnings to the definitive elucidation in 1932. Cholesterol biosynthesis treated in somewhat greater detail covers the period from the 1930s to the 1960s. As a historic contribution, it presents researches previously published in numerous books, reviews, and original papers. The selection of topics, dictated by limits of time and space, is necessarily arbitrary and a personal choice. Readers of this journal will be familiar with the relevant chemical structures. Structural formulas are therefore omitted.

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Year:  1992        PMID： 1519268     DOI： 10.1016/0039-128x(92)90081-j

Source DB:  PubMed          Journal:  Steroids        ISSN： 0039-128X            Impact factor:   2.668


  56 in total

1.  Biosynthesis of terpenoids: YchB protein of Escherichia coli phosphorylates the 2-hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

Authors:  H Lüttgen; F Rohdich; S Herz; J Wungsintaweekul; S Hecht; C A Schuhr; M Fellermeier; S Sagner; M H Zenk; A Bacher; W Eisenreich
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-01       Impact factor: 11.205

Review 2.  Toward biosynthetic design and implementation of Escherichia coli-derived paclitaxel and other heterologous polyisoprene compounds.

Authors:  Ming Jiang; Gregory Stephanopoulos; Blaine A Pfeifer
Journal:  Appl Environ Microbiol       Date:  2012-01-27       Impact factor: 4.792

Review 3.  Regulation of cholesterol homeostasis.

Authors:  Leigh Goedeke; Carlos Fernández-Hernando
Journal:  Cell Mol Life Sci       Date:  2011-10-19       Impact factor: 9.261

4.  Molecular cloning and characterization of a 2C-methyl-D: -erythritol 2,4-cyclodiphosphate synthase gene from Cephalotaxus harringtonia.

Authors:  Junfeng Chen; Ying Xiao; Peng Di; Xiaojing Yu; Wansheng Chen; Lei Zhang
Journal:  Mol Biol Rep       Date:  2008-10-16       Impact factor: 2.316

5.  Biosynthesis of isoprene units: Mössbauer spectroscopy of substrate and inhibitor binding to the [4Fe-4S] cluster of the LytB/IspH enzyme.

Authors:  Annegret Ahrens-Botzong; Karnjapan Janthawornpong; Juliusz A Wolny; Erasmienne Ngouamegne Tambou; Michel Rohmer; Sergiy Krasutsky; C Dale Poulter; Volker Schünemann; Myriam Seemann
Journal:  Angew Chem Int Ed Engl       Date:  2011-10-19       Impact factor: 15.336

6.  Studies on the nonmevalonate pathway to terpenes: the role of the GcpE (IspG) protein.

Authors:  S Hecht; W Eisenreich; P Adam; S Amslinger; K Kis; A Bacher; D Arigoni; F Rohdich
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-18       Impact factor: 11.205

7.  Propagation rate constants for the peroxidation of sterols on the biosynthetic pathway to cholesterol.

Authors:  Connor R Lamberson; Hubert Muchalski; Kari B McDuffee; Keri A Tallman; Libin Xu; Ned A Porter
Journal:  Chem Phys Lipids       Date:  2017-02-05       Impact factor: 3.329

8.  Dimethylallyl pyrophosphate is not the committed precursor of isopentenyl pyrophosphate during terpenoid biosynthesis from 1-deoxyxylulose in higher plants.

Authors:  D Arigoni; W Eisenreich; C Latzel; S Sagner; T Radykewicz; M H Zenk; A Bacher
Journal:  Proc Natl Acad Sci U S A       Date:  1999-02-16       Impact factor: 11.205

9.  Inhibition of sterol biosynthesis reduces tombusvirus replication in yeast and plants.

Authors:  Monika Sharma; Zsuzsanna Sasvari; Peter D Nagy
Journal:  J Virol       Date:  2009-12-16       Impact factor: 5.103

10.  The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: studies on the mechanisms of the reactions catalyzed by IspG and IspH protein.

Authors:  Felix Rohdich; Ferdinand Zepeck; Petra Adam; Stefan Hecht; Johannes Kaiser; Ralf Laupitz; Tobias Gräwert; Sabine Amslinger; Wolfgang Eisenreich; Adelbert Bacher; Duilio Arigoni
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-05       Impact factor: 11.205
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