Literature DB >> 15191004

Positron emission tomography imaging of cell proliferation in oncology.

L M Kenny1, E O Aboagye, P M Price.   

Abstract

Tumour-cell proliferation is a hallmark of the malignant phenotype. Positron emission tomography (PET) offers a unique method of imaging biological and biochemical changes in vivo. Radiolabelled thymidine and thymidine analogues are currently in development as PET tracers. By studying the uptake and kinetics of such compounds using PET, a measure of DNA synthesis and hence cell proliferation can be obtained. Molecular imaging of cellular proliferation with PET is now possible, and has the potential to play an important role in the evaluation of efficacy of new anti-cancer agents.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15191004     DOI： 10.1016/j.clon.2003.10.009

Source DB:  PubMed          Journal:  Clin Oncol (R Coll Radiol)        ISSN： 0936-6555            Impact factor:   4.126


  9 in total

1.  A novel in vitro assay to assess phosphorylation of 3'-[(18)F]fluoro-3'-deoxythymidine.

Authors:  Ning Guo; Jingping Xie; H Charles Manning; Natasha G Deane; M Sib Ansari; Robert J Coffey; John Gore; Ronald R Price; Ronald M Baldwin; J Oliver McIntyre
Journal:  Mol Imaging Biol       Date:  2011-04       Impact factor: 3.488

Review 2.  The role of DNA synthesis imaging in cancer in the era of targeted therapeutics.

Authors:  Sridhar Nimmagadda; Anthony F Shields
Journal:  Cancer Metastasis Rev       Date:  2008-12       Impact factor: 9.264

3.  Preclinical evaluation of a novel c-Met inhibitor in a gastric cancer xenograft model using small animal PET.

Authors:  Stefan Wiehr; Oliver von Ahsen; Lars Röse; Andre Mueller; Julia G Mannheim; Valerie Honndorf; Damaris Kukuk; Gerald Reischl; Bernd J Pichler
Journal:  Mol Imaging Biol       Date:  2013-04       Impact factor: 3.488

Review 4.  Targeted molecular imaging in oncology: focus on radiation therapy.

Authors:  Sridhar Nimmagadda; Eric C Ford; John W Wong; Martin G Pomper
Journal:  Semin Radiat Oncol       Date:  2008-04       Impact factor: 5.934

5.  Comparison of [18F]-tracers in various experimental tumor models by PET imaging and identification of an early response biomarker for the novel microtubule stabilizer patupilone.

Authors:  T Ebenhan; M Honer; S M Ametamey; P A Schubiger; M Becquet; S Ferretti; C Cannet; M Rausch; P M J McSheehy
Journal:  Mol Imaging Biol       Date:  2009-05-22       Impact factor: 3.488

6.  Elevation of radiolabelled thymidine uptake in RIF-1 fibrosarcoma and HT29 colon adenocarcinoma cells after treatment with thymidylate synthase inhibitors.

Authors:  Kawai Yau; Patricia Price; Radhakrishma G Pillai; Eric Aboagye
Journal:  Eur J Nucl Med Mol Imaging       Date:  2006-03-28       Impact factor: 9.236

7.  Preliminary 19F-MRS Study of Tumor Cell Proliferation with 3'-deoxy-3'-fluorothymidine and Its Metabolite (FLT-MP).

Authors:  In Ok Ko; Ki-Hye Jung; Mi Hyun Kim; Kyeung Jun Kang; Kyo Chul Lee; Kyeong Min Kim; Insup Noh; Yong Jin Lee; Sang Moo Lim; Jung Young Kim; Ji-Ae Park
Journal:  Contrast Media Mol Imaging       Date:  2017-09-26       Impact factor: 3.161

8.  Disseminated Skeletal Muscle and Cardiac Metastasis from Squamous Cell Carcinoma of the Lung Detected with FDG and FLT PET/CT.

Authors:  Tarun Kumar Jain; Sampanna Jung Rayamajhi; Rajender Kumar Basher; Dheeraj Gupta; Venkata Nagarjuna Maturu; Bhagwant Rai Mittal
Journal:  World J Nucl Med       Date:  2016-09

Review 9.  Sound Out the Deep Colors: Photoacoustic Molecular Imaging at New Depths.

Authors:  Mucong Li; Nikhila Nyayapathi; Hailey I Kilian; Jun Xia; Jonathan F Lovell; Junjie Yao
Journal:  Mol Imaging       Date:  2020 Jan-Dec       Impact factor: 3.250
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.