| Literature DB >> 15183614 |
Seo-Young Kwak1, Waltraud M Kriven, Matthew A Wallig, Jin-Ho Choy.
Abstract
Uniform, small-sized (100-200 nm), layered double hydroxides (LDH) were prepared by a conventional, wet chemistry method using different aging times of 1 and 3 days as an inorganic drug or gene delivery carrier. The samples prepared had a hexagonal thin, plate-like shape and TEM/SAD electron microscopy of LDH particles indicated that they were single crystals. In vivo testing of empty LDH administered to adult male Sprague Dawley rats was done to evaluate the possibility of using LDH as an injectable drug delivery vehicle.Entities:
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Year: 2004 PMID: 15183614 DOI: 10.1016/j.biomaterials.2004.01.056
Source DB: PubMed Journal: Biomaterials ISSN: 0142-9612 Impact factor: 12.479