Literature DB >> 15183095

Molecular genetics of age-related cataract.

J Fielding Hejtmancik1, Marc Kantorow.   

Abstract

Advances in molecular biological and genetic technology have greatly accelerated elucidation of the genetic contribution to age-related cataract. Epidemiological studies have documented tendencies for cataracts to occur more frequently in relatives of cataract patients than in the general population, genetic studies have demonstrated contributory roles of some specific genes in age related cataract in small populations, and molecular studies have shown changes in expression of specific genes in cataractous lenses. Together, these studies are beginning to provide a conceptual framework for understanding age-related cataracts.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15183095      PMCID： PMC1351356          DOI： 10.1016/j.exer.2004.03.014

Source DB:  PubMed          Journal:  Exp Eye Res        ISSN： 0014-4835            Impact factor:   3.467


  57 in total

1.  Regulation of thioltransferase expression in human lens epithelial cells.

Authors:  N Raghavachari; K Krysan; K Xing; M F Lou
Journal:  Invest Ophthalmol Vis Sci       Date:  2001-04       Impact factor: 4.799

2.  Congenital progressive polymorphic cataract caused by a mutation in the major intrinsic protein of the lens, MIP (AQP0).

Authors:  P Francis; V Berry; S Bhattacharya; A Moore
Journal:  Br J Ophthalmol       Date:  2000-12       Impact factor: 4.638

3.  A genetic factor for age-related cataract: identification and characterization of a novel galactokinase variant, "Osaka," in Asians.

Authors:  Y Okano; M Asada; A Fujimoto; A Ohtake; K Murayama; K J Hsiao; K Choeh; Y Yang; Q Cao; J K Reichardt; S Niihira; T Imamura; T Yamano
Journal:  Am J Hum Genet       Date:  2001-02-23       Impact factor: 11.025

4.  On presentation of the Friedenwald Award of the Association for Research in Vision and Ophthalmology to Dr. Joram Piatigorsky.

Authors:  C Kupfer
Journal:  Invest Ophthalmol Vis Sci       Date:  1987-01       Impact factor: 4.799

5.  Polymorphic glutathione S-transferases as genetic risk factors for senile cortical cataract in Estonians.

Authors:  E Juronen; G Tasa; S Veromann; L Parts; A Tiidla; R Pulges; A Panov; L Soovere; K Koka; A V Mikelsaar
Journal:  Invest Ophthalmol Vis Sci       Date:  2000-07       Impact factor: 4.799

6.  A 5-base insertion in the gammaC-crystallin gene is associated with autosomal dominant variable zonular pulverulent cataract.

Authors:  Z Ren; A Li; B S Shastry; T Padma; R Ayyagari; M H Scott; M M Parks; M I Kaiser-Kupfer; J F Hejtmancik
Journal:  Hum Genet       Date:  2000-05       Impact factor: 4.132

7.  Identification and functional clustering of global gene expression differences between human age-related cataract and clear lenses.

Authors:  John R Hawse; James F Hejtmancik; Quingling Huang; Nancy L Sheets; Douglas A Hosack; Richard A Lempicki; Joseph Horwitz; Marc Kantorow
Journal:  Mol Vis       Date:  2003-10-07       Impact factor: 2.367

8.  Gene expression profiling in human age-related nuclear cataract.

Authors:  Roberta Ruotolo; Francesca Grassi; Riccardo Percudani; Claudio Rivetti; Davide Martorana; Giovanni Maraini; Simone Ottonello
Journal:  Mol Vis       Date:  2003-10-07       Impact factor: 2.367

9.  Up-regulation of osteonectin/SPARC in age-related cataractous human lens epithelia.

Authors:  M Kantorow; J Horwitz; D Carper
Journal:  Mol Vis       Date:  1998-09-17       Impact factor: 2.367

10.  Intercellular communication between epithelial and fiber cells of the eye lens.

Authors:  S Bassnett; J R Kuszak; L Reinisch; H G Brown; D C Beebe
Journal:  J Cell Sci       Date:  1994-04       Impact factor: 5.285
View more
  44 in total

1.  The effect of GSTT1, GSTM1 and GSTP1 gene polymorphisms on the susceptibility of age-related cataract in Chinese Han population.

Authors:  Ruo Qi; Zhimin Gu; Lixiao Zhou
Journal:  Int J Clin Exp Med       Date:  2015-10-15

2.  Gene structure, localization and role in oxidative stress of methionine sulfoxide reductase A (MSRA) in the monkey retina.

Authors:  J W Lee; N V Gordiyenko; M Marchetti; N Tserentsoodol; D Sagher; S Alam; H Weissbach; M Kantorow; I R Rodriguez
Journal:  Exp Eye Res       Date:  2005-12-20       Impact factor: 3.467

Review 3.  Functions of the intermediate filament cytoskeleton in the eye lens.

Authors:  Shuhua Song; Andrew Landsbury; Ralf Dahm; Yizhi Liu; Qingjiong Zhang; Roy A Quinlan
Journal:  J Clin Invest       Date:  2009-07-01       Impact factor: 14.808

4.  Association between DNA repair genes (XPD and XRCC1) polymorphisms and susceptibility to age-related cataract (ARC): a meta-analysis.

Authors:  Lie-rui Zheng; Jian-jun Ma; Dang-xia Zhou; Li-feng An; Ya-qing Zhang
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-06-07       Impact factor: 3.117

5.  Novel Mutations in the Crystallin Gene in Age-Related Cataract Patients from a North Indian Population.

Authors:  Rashmi Patel; Ravish K Zenith; Abhishek Chandra; Akhtar Ali
Journal:  Mol Syndromol       Date:  2017-04-26

6.  Association of G>A transition in exon-1 of alpha crystallin gene in age-related cataracts.

Authors:  S G Bhagyalaxmi; T Padma; G B Reddy; K R K Reddy
Journal:  Oman J Ophthalmol       Date:  2010-01

7.  Autosomal recessive congenital cataract in consanguineous Pakistani families is associated with mutations in GALK1.

Authors:  Afshan Yasmeen; S Amer Riazuddin; Haiba Kaul; Sadia Mohsin; Mohsin Khan; Zaheeruddin A Qazi; Idrees A Nasir; Ahmad U Zafar; Shaheen N Khan; Tayyab Husnain; Javed Akram; J Fielding Hejtmancik; Sheikh Riazuddin
Journal:  Mol Vis       Date:  2010-04-15       Impact factor: 2.367

8.  TXNL6 is a novel oxidative stress-induced reducing system for methionine sulfoxide reductase a repair of α-crystallin and cytochrome C in the eye lens.

Authors:  Lisa A Brennan; Wanda Lee; Marc Kantorow
Journal:  PLoS One       Date:  2010-11-04       Impact factor: 3.240

9.  Polymorphisms of the WRN gene and DNA damage of peripheral lymphocytes in age-related cataract in a Han Chinese population.

Authors:  Shengqun Jiang; Nan Hu; Jing Zhou; Junfang Zhang; Ruifang Gao; Jianyan Hu; Huaijin Guan
Journal:  Age (Dordr)       Date:  2013-01-20

10.  EPHA2 is associated with age-related cortical cataract in mice and humans.

Authors:  Gyungah Jun; Hong Guo; Barbara E K Klein; Ronald Klein; Jie Jin Wang; Paul Mitchell; Hui Miao; Kristine E Lee; Tripti Joshi; Matthias Buck; Preeti Chugha; David Bardenstein; Alison P Klein; Joan E Bailey-Wilson; Xiaohua Gong; Tim D Spector; Toby Andrew; Christopher J Hammond; Robert C Elston; Sudha K Iyengar; Bingcheng Wang
Journal:  PLoS Genet       Date:  2009-07-31       Impact factor: 5.917
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.