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229 in total

1. Mutation analysis of the presenilin 1 N-terminal domain reveals a broad spectrum of gamma-secretase activity toward amyloid precursor protein and other substrates.

Authors: Ping Gong; Kulandaivelu S Vetrivel; Phuong D Nguyen; Xavier Meckler; Haipeng Cheng; Maria Z Kounnas; Steven L Wagner; Angèle T Parent; Gopal Thinakaran
Journal: J Biol Chem Date: 2010-10-04 Impact factor: 5.157

Review 2. γ-Secretase-regulated mechanisms similar to notch signaling may play a role in signaling events, including APP signaling, which leads to Alzheimer's disease.

Authors: Kohzo Nakayama; Hisashi Nagase; Chang-Sung Koh; Takeshi Ohkawara
Journal: Cell Mol Neurobiol Date: 2011-04-23 Impact factor: 5.046

Review 3. Physiological functions of the amyloid precursor protein secretases ADAM10, BACE1, and presenilin.

Authors: Johannes Prox; Andrea Rittger; Paul Saftig
Journal: Exp Brain Res Date: 2011-11-27 Impact factor: 1.972

4. Purification and characterization of the human γ-secretase activating protein.

Authors: Catherine L Deatherage; Arina Hadziselimovic; Charles R Sanders
Journal: Biochemistry Date: 2012-06-13 Impact factor: 3.162

Review 5. Targeting Notch to target cancer stem cells.

Authors: Antonio Pannuti; Kimberly Foreman; Paola Rizzo; Clodia Osipo; Todd Golde; Barbara Osborne; Lucio Miele
Journal: Clin Cancer Res Date: 2010-06-08 Impact factor: 12.531

6. And four equals one: presenilin takes the gamma-secretase role by itself.

Authors: Christian B Lessard; Steven L Wagner; Edward H Koo
Journal: Proc Natl Acad Sci U S A Date: 2010-12-06 Impact factor: 11.205

Review 7. Presenilin: RIP and beyond.

Authors: Matthew R Hass; Chihiro Sato; Raphael Kopan; Guojun Zhao
Journal: Semin Cell Dev Biol Date: 2008-11-27 Impact factor: 7.727

Review 8. Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders.

Authors: Vijay K Ramanan; Andrew J Saykin
Journal: Am J Neurodegener Dis Date: 2013-09-18

Review 9. Toward the structure of presenilin/γ-secretase and presenilin homologs.

Authors: Michael S Wolfe
Journal: Biochim Biophys Acta Date: 2013-12

10. Inhibition of gamma-secretases alters both proliferation and differentiation of mesenchymal stem cells.

Authors: S Vujovic; S R Henderson; A M Flanagan; M O Clements
Journal: Cell Prolif Date: 2007-04 Impact factor: 6.831