BACKGROUND: There is a significant relationship between calcification of the aortic arch (Arch) detected by chest X-ray examination and coronary artery disease (CAD), but the relationship between risk factors, CAD and aortic calcification detected during a mass screening program using a mobile helical computed tomography (CT) unit remains unknown. METHODS AND RESULTS: In total 2,623 subjects (1,347 men, and 1,276 women; mean age, 52.9+/-13.8) underwent an examination for lung cancer and tuberculosis using a mobile helical CT unit. The frequency of calcification was 19.6% in the Arch, 2.7% in the ascending aorta, and 10.1% in the descending aorta, values that were positively associated with age in both genders. Hypertension and smoking were significantly related to calcification of the thoracic aorta. There was a significant relationship between CAD and aortic calcification. The odds ratio of aortic calcification for patients with CAD increased as the number of calcified segments increased. CONCLUSIONS: These results suggest that detection of calcification in the thoracic aorta during a mass chest screening using a mobile helical CT unit can be used to evaluate the risk of CAD.
BACKGROUND: There is a significant relationship between calcification of the aortic arch (Arch) detected by chest X-ray examination and coronary artery disease (CAD), but the relationship between risk factors, CAD and aortic calcification detected during a mass screening program using a mobile helical computed tomography (CT) unit remains unknown. METHODS AND RESULTS: In total 2,623 subjects (1,347 men, and 1,276 women; mean age, 52.9+/-13.8) underwent an examination for lung cancer and tuberculosis using a mobile helical CT unit. The frequency of calcification was 19.6% in the Arch, 2.7% in the ascending aorta, and 10.1% in the descending aorta, values that were positively associated with age in both genders. Hypertension and smoking were significantly related to calcification of the thoracic aorta. There was a significant relationship between CAD and aortic calcification. The odds ratio of aortic calcification for patients with CAD increased as the number of calcified segments increased. CONCLUSIONS: These results suggest that detection of calcification in the thoracic aorta during a mass chest screening using a mobile helical CT unit can be used to evaluate the risk of CAD.
Authors: Ibrahim Aboshady; Dianna D Cody; Evan M Johnson; Amir Gahremanpour; Deborah Vela; Kamal G Khalil; Herbert L Dupont; James T Willerson; L Maximilian Buja; Gregory W Gladish Journal: Int J Cardiol Date: 2010-12-24 Impact factor: 4.164
Authors: Isac C Thomas; Robyn L McClelland; Erin D Michos; Matthew A Allison; Nketi I Forbang; W T Longstreth; Wendy S Post; Nathan D Wong; Matthew J Budoff; Michael H Criqui Journal: Atherosclerosis Date: 2017-09-07 Impact factor: 5.162
Authors: Matthew J Budoff; Khurram Nasir; Ronit Katz; Junichiro Takasu; J Jeffery Carr; Nathan D Wong; Matthew Allison; Joao A C Lima; Robert Detrano; Roger S Blumenthal; Richard Kronmal Journal: Atherosclerosis Date: 2010-11-26 Impact factor: 5.162
Authors: Hagen Kälsch; Nils Lehmann; Stefan Möhlenkamp; Cornelia Hammer; Amir A Mahabadi; Susanne Moebus; Axel Schmermund; Andreas Stang; Marcus Bauer; Karl-Heinz Jöckel; Raimund Erbel Journal: Int J Cardiovasc Imaging Date: 2012-04-22 Impact factor: 2.357
Authors: Isac C Thomas; Robyn L McClelland; Matthew A Allison; Joachim H Ix; Erin D Michos; Nketi I Forbang; Wendy S Post; Nathan D Wong; Matthew J Budoff; Michael H Criqui Journal: Eur Heart J Cardiovasc Imaging Date: 2018-12-01 Impact factor: 6.875
Authors: Mirza Mujadil Ahmad; Syed Haris Ahmed Pir; Mustafa Noor Muhammad; Sharmeen Hussaini; Immad Arif Kiani; Mirza Nubair Ahmad; Imaad Razzaque; Muhammad Nabeel Syed; Rafath Ullah; Suhail Allaqaband; Anjan Gupta; Steven C Port; Khawaja Afzal Ammar Journal: J Patient Cent Res Rev Date: 2017-08-10
Authors: Pim A de Jong; Willem E Hellings; Richard A P Takx; Ivana Išgum; Joost A van Herwaarden; Willem P Th M Mali Journal: PLoS One Date: 2014-07-08 Impact factor: 3.240