Literature DB >> 15167933

Human genes that limit AIDS.

Stephen J O'Brien1, George W Nelson.   

Abstract

Discernable genetic variation among people and populations has an important role in infectious disease epidemics, including that of acquired immune deficiency syndrome (AIDS). Genetic association analysis of several large AIDS cohorts implicate 14 AIDS restriction genes, polymorphic variants in loci that regulate HIV-1 cell entry, acquired and innate immunity, and cytokine defenses to HIV-1. The influence and translational impact of these genes on individual and population sensitivity to AIDS is considerable.

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Year:  2004        PMID： 15167933     DOI： 10.1038/ng1369

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  127 in total

1.  Genetic factors associated with slow progression of HIV among perinatally-infected Indian children.

Authors:  Riya Pal Chaudhuri; Ujjwal Neogi; Shwetha D Rao; Anita Shet
Journal:  Indian Pediatr       Date:  2014-10       Impact factor: 1.411

2.  Effect of host genetics on incidence of HIV neuroretinal disorder in patients with AIDS.

Authors:  Efe Sezgin; Sher L Hendrickson; Douglas A Jabs; Mark L Van Natta; Richard A Lewis; Jennifer L Troyer; Stephen J O'Brien
Journal:  J Acquir Immune Defic Syndr       Date:  2010-08       Impact factor: 3.731

3.  Cytomegalovirus retinitis and the acquired immunodeficiency syndrome--bench to bedside: LXVII Edward Jackson Memorial Lecture.

Authors:  Douglas A Jabs
Journal:  Am J Ophthalmol       Date:  2010-12-18       Impact factor: 5.258

Review 4.  HLA and disease.

Authors:  Yogita Ghodke; Kalpana Joshi; Arvind Chopra; Bhushan Patwardhan
Journal:  Eur J Epidemiol       Date:  2005       Impact factor: 8.082

5.  Searching for signals of evolutionary selection in 168 genes related to immune function.

Authors:  Emily C Walsh; Pardis Sabeti; Holli B Hutcheson; Ben Fry; Stephen F Schaffner; Paul I W de Bakker; Patrick Varilly; Alejandro A Palma; Jessica Roy; Richard Cooper; Cheryl Winkler; Yi Zeng; Guy de The; Eric S Lander; Stephen O'Brien; David Altshuler
Journal:  Hum Genet       Date:  2005-12-14       Impact factor: 4.132

6.  The role of race and gender in T cell responses in children perinatally infected with HIV-1.

Authors:  Andrea Kovacs; Maria C Villacres
Journal:  J Infect Dis       Date:  2005-10-05       Impact factor: 5.226

7.  Simian immunodeficiency virus SIVmac239 infection of major histocompatibility complex-identical cynomolgus macaques from Mauritius.

Authors:  Roger W Wiseman; Jason A Wojcechowskyj; Justin M Greene; Alex J Blasky; Tobias Gopon; Taeko Soma; Thomas C Friedrich; Shelby L O'Connor; David H O'Connor
Journal:  J Virol       Date:  2006-10-11       Impact factor: 5.103

8.  Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.

Authors:  James R Cerhan; Sophia Wang; Matthew J Maurer; Stephen M Ansell; Susan M Geyer; Wendy Cozen; Lindsay M Morton; Scott Davis; Richard K Severson; Nathaniel Rothman; Charles F Lynch; Sholom Wacholder; Stephen J Chanock; Thomas M Habermann; Patricia Hartge
Journal:  Blood       Date:  2007-02-27       Impact factor: 22.113

9.  Extended IL10 haplotypes and their association with HIV progression to AIDS.

Authors:  T K Oleksyk; S Shrestha; A L Truelove; J J Goedert; S M Donfield; J Phair; S Mehta; S J O'Brien; M W Smith
Journal:  Genes Immun       Date:  2009-03-19       Impact factor: 2.676

10.  A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model.

Authors:  Saki Shimizu; Patrick Hong; Balamurugan Arumugam; Lauren Pokomo; Joshua Boyer; Naoya Koizumi; Panyamol Kittipongdaja; Angela Chen; Greg Bristol; Zoran Galic; Jerome A Zack; Otto Yang; Irvin S Y Chen; Benhur Lee; Dong Sung An
Journal:  Blood       Date:  2009-12-17       Impact factor: 22.113
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