Literature DB >> 15166538

An IL-8 gene promoter polymorphism is associated with the risk of the development of AIDS-related Kaposi's sarcoma: a case-control study.

Antoinette C van der Kuyl1, Abeltje M Polstra, Gerrit Jan Weverling, Fokla Zorgdrager, Remco van den Burg, Marion Cornelissen.   

Abstract

In a case-control study, we studied the effect of a single nucleotide polymorphism in the IL-8 promoter on the risk of the development of AIDS-related Kaposi's sarcoma (KS). KS developed in 46% of individuals with the TT genotype and in 66% of AA/AT genotypes (P=0.038). Patients with TT genotype were rarely affected with visceral KS (7% versus 36%; P=0.06), which suggests that carriers of the TT genotype are protected from (severe) KS development.

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Year:  2004        PMID： 15166538     DOI： 10.1097/00002030-200405210-00016

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  10 in total

1.  -251 T/A polymorphism of the interleukin-8 gene and cancer risk: a HuGE review and meta-analysis based on 42 case-control studies.

Authors:  Na Wang; Rongmiao Zhou; Chunmei Wang; Xiaoqing Guo; Zhifeng Chen; Shan Yang; Yan Li
Journal:  Mol Biol Rep       Date:  2011-06-17       Impact factor: 2.316

2.  Correlation of polymorphism of IL-8 and MMP-7 with occurrence and lymph node metastasis of early stage cervical cancer.

Authors:  Suhui Wu; Shi Lu; Huijuan Tao; Li Zhang; Weifeng Lin; Haixia Shang; Jun Xie
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2011-02-19

3.  Risk modification of colorectal cancer susceptibility by interleukin-8 -251T>A polymorphism in Malaysians.

Authors:  Mohd Aminudin Mustapha; Siti Nurfatimah Mohd Shahpudin; Ahmad Aizat Abdul Aziz; Ravindran Ankathil
Journal:  World J Gastroenterol       Date:  2012-06-07       Impact factor: 5.742

4.  Polymorphisms in Host Immunity-Modulating Genes and Risk of Invasive Aspergillosis: Results from the AspBIOmics Consortium.

Authors:  C B Lupiañez; L M Canet; A Carvalho; L Alcazar-Fuoli; J Springer; M Lackner; J Segura-Catena; A Comino; C Olmedo; R Ríos; A Fernández-Montoya; M Cuenca-Estrella; C Solano; M Á López-Nevot; C Cunha; A Oliveira-Coelho; T Villaescusa; L Fianchi; J M Aguado; L Pagano; E López-Fernández; L Potenza; M Luppi; C Lass-Flörl; J Loeffler; H Einsele; L Vazquez; M Jurado; J Sainz
Journal:  Infect Immun       Date:  2015-12-14       Impact factor: 3.441

Review 5.  The chemokine network. II. On how polymorphisms and alternative splicing increase the number of molecular species and configure intricate patterns of disease susceptibility.

Authors:  R Colobran; R Pujol-Borrell; M P Armengol; M Juan
Journal:  Clin Exp Immunol       Date:  2007-10       Impact factor: 4.330

6.  A promoter SNP rs4073T>A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode.

Authors:  Mi-Hyun Ahn; Byung-Lae Park; Shin-Hwa Lee; Sung-Woo Park; Jong-Sook Park; Do-Jin Kim; An-Soo Jang; Jai-Soung Park; Hwa-Kyun Shin; Soo-Taek Uh; Yang-Ki Kim; Young Whan Kim; Sung Koo Han; Ki-Suck Jung; Kye Young Lee; Sung Hwan Jeong; Jeong Woong Park; Byoung Whui Choi; In Won Park; Man Pyo Chung; Hyoung Doo Shin; Jin Woo Song; Dong Soon Kim; Choon-Sik Park; Young-Soo Shim
Journal:  Respir Res       Date:  2011-06-08

Review 7.  Dermatological Complications After Solid Organ Transplantation.

Authors:  Luigi Naldi; Anna Venturuzzo; Pietro Invernizzi
Journal:  Clin Rev Allergy Immunol       Date:  2018-02       Impact factor: 10.817

8.  Positive association between Interleukin-8 -251A > T polymorphism and susceptibility to gastric carcinogenesis: a meta-analysis.

Authors:  Daye Cheng; Yiwen Hao; Wenling Zhou; Yiran Ma
Journal:  Cancer Cell Int       Date:  2013-10-22       Impact factor: 5.722

Review 9.  Evidence for altered host genetic factors in KSHV infection and KSHV-related disease development.

Authors:  Melissa J Blumenthal; Elena Maria Cornejo Castro; Denise Whitby; Arieh A Katz; Georgia Schäfer
Journal:  Rev Med Virol       Date:  2020-10-11       Impact factor: 6.989

10.  Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections.

Authors:  Robert Newton; Denise Whitby; Inês Barroso; Neneh Sallah; Wendell Miley; Nazzarena Labo; Tommy Carstensen; Segun Fatumo; Deepti Gurdasani; Martin O Pollard; Alexander T Dilthey; Alexander J Mentzer; Vickie Marshall; Elena M Cornejo Castro; Cristina Pomilla; Elizabeth H Young; Gershim Asiki; Martin L Hibberd; Manjinder Sandhu; Paul Kellam
Journal:  Nat Commun       Date:  2020-07-31       Impact factor: 14.919
  10 in total

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