| Literature DB >> 15164008 |
Tobias von der Haar1, John D Gross, Gerhard Wagner, John E G McCarthy.
Abstract
Eukaryotic initiation factor 4E (eIF4E) has central roles in the control of several aspects of post-transcriptional gene expression and thereby affects developmental processes. It is also implicated in human diseases. This review explores the relationship between structural, biochemical and biophysical aspects of eIF4E and its function in vivo, including both long-established roles in translation and newly emerging ones in nuclear export and mRNA decay pathways.Entities:
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Year: 2004 PMID： 15164008 DOI： 10.1038/nsmb779
Source DB: PubMed Journal: Nat Struct Mol Biol ISSN： 1545-9985 Impact factor: 15.369