| Literature DB >> 15150695 |
Cheng-Hsin Lu1, Cherry Guan-Ju Lin1, Lichih Huang1, Ling-Mei Wang1, Lawrence Shih-Hsin Wu2.
Abstract
To evaluate basic informativeness of commercially available microsatellite markers in theTaiwanese population, 190 unrelated Taiwanese children were genotyped using ABI PRISM Linkage Mapping Set-HD5. The average heterozygosity in Taiwanese was slightly lower than that in Caucasians among these 811 microsatellite markers. There were 50 marker loci with heterozygosities lower than 50%. Moreover, allelic distributions at many of the loci were significantly different in two ethnic groups. The results reported here represent a valuable database for disease genes mapping in the Taiwanese population. This database can be easily accessed at the Web site of Vita Genomics, Inc. (http://www.vitagenomics.com/str.html).Entities:
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Year: 2004 PMID: 15150695 DOI: 10.1007/s10038-004-0152-5
Source DB: PubMed Journal: J Hum Genet ISSN: 1434-5161 Impact factor: 3.172