Literature DB >> 15149683

3,3(')-Oxybis(dimethoxytrityl chloride) (O-DMTCl): synthesis and applications of a novel bifunctional protecting group.

Natsuhisa Oka1, Yogesh S Sanghvi, Emmanuel A Theodorakis.   

Abstract

3,3(')- Oxybis(dimethoxytrityl chloride) (O-DMTCl) was synthesized as a novel, acid-labile bifunctional protecting reagent. The reactions of O-DMTCl with base-protected ribonucleosides afforded unexpectedly 2('),5(')-cyclic protected ribonucleosides in addition to the expected 3('),5(')-cyclic protected ribonucleosides in good yields.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15149683     DOI: 10.1016/j.bmcl.2004.03.097

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Tritylation of Alcohols under Mild Conditions without Using Silver Salts.

Authors:  Shahien Shahsavari; Jinsen Chen; Travis Wigstrom; James Gooding; Alexander Gauronskas; Shiyue Fang
Journal:  Tetrahedron Lett       Date:  2016-07-18       Impact factor: 2.415

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.