Literature DB >> 15149023

Retrograde transport of cholera toxin into the ER of host cells.

Wayne I Lencer1.   

Abstract

Cholera toxin moves from the plasma membrane to the ER of host cells to cause disease. Here we discuss recent studies on the mechanism of transport from plasma membrane to the ER and on the reactions that unfold and retrotranslocate a portion of the toxin to the cytosol where toxicity is induced.

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Year:  2004        PMID： 15149023     DOI： 10.1078/1438-4221-00293

Source DB:  PubMed          Journal:  Int J Med Microbiol        ISSN： 1438-4221            Impact factor:   3.473


  11 in total

1.  Flying kites on slippery slopes at Keystone. Symposium on Lipid Rafts and Cell Function.

Authors:  Satvajit Mayor; Antonella Viola; Radu V Stan; Miguel A del Pozo
Journal:  EMBO Rep       Date:  2006-10-20       Impact factor: 8.807

2.  Gas phase characterization of the noncovalent quaternary structure of cholera toxin and the cholera toxin B subunit pentamer.

Authors:  Jonathan P Williams; Daniel C Smith; Brian N Green; Brian D Marsden; Keith R Jennings; Lynne M Roberts; James H Scrivens
Journal:  Biophys J       Date:  2006-02-03       Impact factor: 4.033

3.  A novel approach for targeted delivery to motoneurons using cholera toxin-B modified protocells.

Authors:  Maria A Gonzalez Porras; Paul N Durfee; Ashley M Gregory; Gary C Sieck; C Jeffrey Brinker; Carlos B Mantilla
Journal:  J Neurosci Methods       Date:  2016-09-15       Impact factor: 2.390

Review 4.  Facing glycosphingolipid-Shiga toxin interaction: dire straits for endothelial cells of the human vasculature.

Authors:  Andreas Bauwens; Josefine Betz; Iris Meisen; Björn Kemper; Helge Karch; Johannes Müthing
Journal:  Cell Mol Life Sci       Date:  2012-07-06       Impact factor: 9.261

5.  Order-disorder-order transitions mediate the activation of cholera toxin.

Authors:  Ravi S Ampapathi; Andrea L Creath; Dianne I Lou; John W Craft; Steven R Blanke; Glen B Legge
Journal:  J Mol Biol       Date:  2008-01-05       Impact factor: 5.469

6.  Analysis of lectin binding to glycolipid complexes using combinatorial glycoarrays.

Authors:  Simon Rinaldi; Kathryn M Brennan; Carl S Goodyear; Colin O'Leary; Giampietro Schiavo; Paul R Crocker; Hugh J Willison
Journal:  Glycobiology       Date:  2009-04-06       Impact factor: 4.313

7.  Design, synthesis, and evaluation of bisubstrate analog inhibitors of cholera toxin.

Authors:  Guangtao Zhang
Journal:  Bioorg Med Chem Lett       Date:  2008-05-17       Impact factor: 2.823

8.  A mutational analysis of residues in cholera toxin A1 necessary for interaction with its substrate, the stimulatory G protein Gsα.

Authors:  Michael G Jobling; Lisa F Gotow; Zhijie Yang; Randall K Holmes
Journal:  Toxins (Basel)       Date:  2015-03-18       Impact factor: 4.546

9.  Role of the Antigen Capture Pathway in the Induction of a Neutralizing Antibody Response to Anthrax Protective Antigen.

Authors:  Anita Verma; Miriam M Ngundi; Gregory A Price; Kazuyo Takeda; James Yu; Drusilla L Burns
Journal:  mBio       Date:  2018-02-27       Impact factor: 7.867

10.  Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry.

Authors:  Parikshit Bagchi; Mauricio Torres; Ling Qi; Billy Tsai
Journal:  Nat Commun       Date:  2020-02-28       Impact factor: 14.919
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