| Literature DB >> 15144299 |
M M R F Struys1, M P L A Bouche, G Rolly, Y D I Vandevivere, D Dyzers, W Goeteyn, L F M Versichelen, J F P Van Bocxlaer, E P Mortier.
Abstract
Two new generation carbon dioxide absorbents, DrägerSorb Free and Amsorb Plus, were studied in vitro for formation of compound A or carbon monoxide, during minimal gas flow (500 ml x min(-1)) with sevoflurane or desflurane. Compound A was assessed by gas chromatography/mass spectrometry and carbon monoxide with continuous infrared spectrometry. Fresh and dehydrated absorbents were studied. Mean (SD) time till exhaustion (inspiratory carbon dioxide concentration >or= 1 kPa) with fresh absorbents was longer with DrägerSorb Free (1233 (55) min) than with Amsorb Plus (1025 (55) min; p < 0.01). For both absorbents, values of compound A were < 1 ppm and therefore below clinically significant levels, but were up to 0.25 ppm higher with DrägerSorb Free than with Amsorb Plus. Using dehydrated absorbents, values of compound A were about 50% lower than with fresh absorbents and were identical for DrägerSorb Free and Amsorb Plus. With dehydrated absorbents, no detectable carbon monoxide was found with desflurane.Entities:
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Year: 2004 PMID： 15144299 DOI： 10.1111/j.1365-2044.2004.03704.x
Source DB: PubMed Journal: Anaesthesia ISSN： 0003-2409 Impact factor: 6.955